ID A0A1S3ZJZ0_TOBAC Unreviewed; 640 AA.
AC A0A1S3ZJZ0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein AGD3-like isoform X3 {ECO:0000313|RefSeq:XP_016464840.1};
GN Name=LOC107787736 {ECO:0000313|RefSeq:XP_016464840.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016464840.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016464840.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016464840.1; XM_016609354.1.
DR AlphaFoldDB; A0A1S3ZJZ0; -.
DR GeneID; 107787736; -.
DR OrthoDB; 1449795at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07606; BAR_SFC_plant; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR035670; AGD1/2/3/4_BAR_plant.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF403; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD3-LIKE; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 294..433
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 497..580
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 442..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 72809 MW; 55E7CAD8590609F0 CRC64;
MQEGKMLFAR LDDSPMFRQQ IQSMEECAET LRDKCLKFYK GSRKYTEGLG EAYDRDIAFS
SSLETFGGGR HDPISVAFGG PDMAKFAIAL REIGTYKEVL RSQVEHVLND RLLHLATIDL
QDVKEARKRF DKANVAYDQV REKFLSLRKS TRMDIAAAIE EELYNARLTF EQARFNLVGA
HSAVEAKKKY ELLEAVGSMM DTHLRYFKQG YELLHQMEPY INQVLAYSQK ARESSMYEQA
ALNERMQEYR RKIDQERRRS FNGSPNGDVT QPFSRSSHKL IEAVMQSAAE GKVQTIKQGY
LSKRSSNLRG DWKRRFFVLD SRGMLYYYRK QLSRPSFQGS GSPLLSHRCS SPEPGAGLLS
RWLSSHYHGG VHEEKTVARH TVNLLTSTIK ADADQSDLRF CFRIISPTKN YTLQAESAAE
QMDWIEKITG VISSLLSSQT PERHFSASPT SESSSIGSPI DHDQRATEEY TSGRDLTGRS
FIRPSKSSVH ILSTKIEKPV EALKRIPGND KCADCGAPGP EWASLNLGIL ICIECSGVHR
NFGVHISKVR SLKLDVKVWE PSVITFFEAL GNVFVNSIWE ELLHARKTFQ ADEIPMRFFE
SEKHKQFFGK PSYADHISVK EKFIHAKVGG HRTFCLRVTV
//
