ID A0A1S4A074_TOBAC Unreviewed; 570 AA.
AC A0A1S4A074;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN Name=LOC107792301 {ECO:0000313|RefSeq:XP_016469990.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016469990.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016469990.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR RefSeq; XP_016469990.1; XM_016614504.1.
DR AlphaFoldDB; A0A1S4A074; -.
DR GeneID; 107792301; -.
DR OrthoDB; 3014064at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR024632; PLipase_D_C.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF137; PHOSPHOLIPASE D ALPHA 4; 1.
DR Pfam; PF12357; PLD_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 109..146
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 416..443
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 570 AA; 65691 MW; D6F07ABE6720B270 CRC64;
MEGKYKCFHG TLEVSIFRAT SHKSSIPLKV RDPSTEIMHA KGVKLGELLK RKAEEGVAVR
IMLWDDETSL PIIKNKGVMR THDEDSLAYF RDTKVVCKLV PRLHHKLPSF FAHHQKVITV
DSRSHLSSTS REITSFIGGL DLCDGRYDTE EHSLFKTLNT ESHCYDFYQT SLSGASLHKG
GPREPWHDAH ARVTGQAAMD ILNNFEQRWN KQIGPSLLIP IRSIPELSNQ PNMASTDRDW
NVQVFRSIDH VSACPLPMNM PIERSIHEAY VEAIRRADRF IYIENQYFIG ACHLWEQDQH
CGCRNLIPIE IALKVANKIK AKERFAVYIV IPMWPEGLPE SDSVQDILHW TRETMKMMYK
FIGEAIKESG EPGHPRDYLN FFCLANREEE FKGEFVPPYS PHPESQYWKA QKKRRFMVYV
HSKLMIVDDT YLLIGSANIN QRSMDGQRDT EIAIGCYQSK SEEGDIDQRD VHAYRMSLWY
EHTAKAEQVF QEPQSLECVQ KIRSIGDQLW KIYDQDEVED MKGVHLVTYP VNVTAEGHVV
DIMERNGHFP DTEALIKGRR SKVLAPTITT
//
