ID A0A1S4A233_TOBAC Unreviewed; 1042 AA.
AC A0A1S4A233;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Histone-lysine N-methyltransferase ATX4-like isoform X4 {ECO:0000313|RefSeq:XP_016470654.1};
GN Name=LOC107792888 {ECO:0000313|RefSeq:XP_016470654.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016470654.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016470654.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016470654.1; XM_016615168.1.
DR AlphaFoldDB; A0A1S4A233; -.
DR GeneID; 107792888; -.
DR OrthoDB; 304343at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR CDD; cd15663; ePHD_ATX3_4_5_like; 1.
DR CDD; cd15495; PHD_ATX3_4_5_like; 1.
DR CDD; cd15517; PHD_TCF19_like; 1.
DR CDD; cd20143; PWWP_AtATX3-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR041955; ATX3/4/5_ePHD.
DR InterPro; IPR042011; ATX3/4/5_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR025780; Hist-Lys_N-MeTrfase_ATX.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF92; HISTONE-LYSINE N-METHYLTRANSFERASE ATX3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51566; SAM_MT43_TRX_MLL; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 231..299
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 417..473
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 605..656
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 659..774
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 900..1017
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1026..1042
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
SQ SEQUENCE 1042 AA; 118557 MW; 29A5CAC1D5B03022 CRC64;
MRRKMFVKRT VKVEMPKLKR CKTEEDEKLK TEELFTVPIK ELEDYRTSLV DSFCREALSY
AGEVESSFAL AGASRSLEKA FEVHNHNKPP LLKSSRGRIQ VLPSKFNDSV LPSWKKEQNP
EEQELLCLSE KDEGAVLPHK KRFKSEGYNQ RMQHLPSSVI FEDREFGYMQ SKDCSRSSVT
SVCEGGGSSA LMESGGCESR ARRGFAREDS NYMKEKVGKK KDFFEPGDFV LGDIVWAKCG
KNYPAWPAVV IDPLWQAPEA VLRACVPGTL CVMFYGYSKS GLRDYGWVKA GMIFPFQEYV
DRFQGQTKLY GSRPSDFHMA IEEAILAEHG YSDKRPEMEQ ETSPATNDSG IEEATGSNQE
LDLCFSDQQD GYDKRKDTRR CDSCYLIFPF RTMKKVKDTM SKAQFFCGHC VKLRKSKQYC
GICKNIWHHS DGGDWVCCDG CDVWVHVECA DISSNVLKNL QNTDYFCPEC KANSNKKASV
SEQRGAKARL KESNGSLMPD KITVVCTGVE GIYYPDLHLV QCKCGSCGTR KLTLSEWERH
TGCRAKKWKC SVKVKGSMIT LDQLLSDHNA YNFTYQKFTY QKLDHQQLFA FLREKYEPVH
AKWTTERCAI CRWVEDWDYN KIIICNRCQI AVHQECYGVS NLQDFASWVC RACETPEIER
ECCLCPVKGG ALKPTDIDSL WVHVTCAWFR PEVAFHNADK MEPAVGLLRI PPNTFLKACV
ICKQVHGSCT QCCKCATNFH AMCALRAGYH MELNCSEKNG VQITRWLSYC AFHRAPDTDN
VLVMRTPFGV FSTKSLVERQ SQEHSLRGRR LISSKALEFP EASDAGTSSF EPFSAARCRI
FQRSSNKRAG QVALFHRLMG PRHHSLEAID CLNSQELAGD VKAFSTLKER LIHLQTTESR
RVCFGKSGIH GWGLFARRSI QEGEMVLEYR GEQVRRSVAD LREARYRLEG KDCYLFKVSE
EVVIDATNKG NIGRLINHSC MPNCYARIMS LGEEESRIVL IAKSNVSAGD ELTYDYLFDP
DEHDDLKVPC LCGAPNCRKF MN
//
