ID   A0A1S4A4E2_TOBAC        Unreviewed;       725 AA.
AC   A0A1S4A4E2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Uncharacterized protein LOC107793595 {ECO:0000313|RefSeq:XP_016471459.1};
GN   Name=LOC107793595 {ECO:0000313|RefSeq:XP_016471459.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016471459.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016471459.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PDCD4 family.
CC       {ECO:0000256|ARBA:ARBA00005497}.
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DR   RefSeq; XP_016471459.1; XM_016615973.1.
DR   AlphaFoldDB; A0A1S4A4E2; -.
DR   SMR; A0A1S4A4E2; -.
DR   STRING; 4097.A0A1S4A4E2; -.
DR   PaxDb; 4097-A0A1S4A4E2; -.
DR   GeneID; 107793595; -.
DR   KEGG; nta:107793595; -.
DR   OMA; WLDSSFC; -.
DR   OrthoDB; 1217702at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 4.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR   InterPro; IPR039778; PDCD4.
DR   PANTHER; PTHR12626:SF2; MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 2; 1.
DR   PANTHER; PTHR12626; PROGRAMMED CELL DEATH 4; 1.
DR   Pfam; PF02847; MA3; 4.
DR   SMART; SM00544; MA3; 4.
DR   SUPFAM; SSF48371; ARM repeat; 4.
DR   PROSITE; PS51366; MI; 4.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          131..252
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   DOMAIN          295..416
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   DOMAIN          430..551
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   DOMAIN          598..717
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   REGION          1..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  81319 MW;  882EE12118F28D38 CRC64;
     MEFTDGKLSN EHKEQLRSAS ESADPLSVSP LQISPLKVSP KSPRSPKSPR SPGDRQSKPV
     TERGSPLKNR RNSHSPRDGR PKKGGCGGKG TWGGLMDTDD VHAIDPNDPN YTSSEDIERT
     SSKDMIATFE DYKKKAIILV EEYFQNDDIT STANELRELG TSSYDFYFVK KLVSMAMDRH
     DKEKEMAAVL LSALYAEVIK PQQVYKGFSK LLESADDFIV DIPDAIDILA LFIARAVVDD
     ILPPAFLAKA NSSLPKDSKG IEVIKRAEKS YLSAPLHAEI IERRWGGSKN KTVEDVKDKI
     NNLLIEYVVS GEKKEAFRCI KDLNMRFFHH EIVKRAIIMV MEKQQAENRL LDLLKKAAEE
     GLINSSQLSK GINRIIDNID DLSLDIPNAR VILQSIISKA ASEGWLCISS LKSLSKEIEK
     QEIDEKLVKE FKLKAQSMIK EYFLSGEIVE VSRFLESENS SCLAELNAIF VKKLITLAMD
     RKNREKEMAS VLLSSVCFPA DDVVNGFVML IDSAEDTALD IPIVVEDLAM FLARAEVDEV
     LTPQHMEEIG SQFFEPNSIG NKVVLMAKSL LKGRLSGERI LRCWGGGGSS SNGWAIEDVK
     DKIRKLLEEF ESGGDAKEAY RCIKELGMPF FHHEVVKKSL VIIIEKKNER LWGFLKECFS
     MGLITMYQMT KGFARVAESL DDLALDVPDA EKQFKDYVER AKVEGWLDST VSFNRLGHSM
     ENGFC
//