ID   A0A1S4A526_TOBAC        Unreviewed;       867 AA.
AC   A0A1S4A526;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Clathrin interactor EPSIN 2-like isoform X2 {ECO:0000313|RefSeq:XP_016471748.1};
GN   Name=LOC107793819 {ECO:0000313|RefSeq:XP_016471748.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016471748.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016471748.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC       {ECO:0000256|ARBA:ARBA00004132}. Vesicle
CC       {ECO:0000256|ARBA:ARBA00004373}.
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DR   RefSeq; XP_016471748.1; XM_016616262.1.
DR   AlphaFoldDB; A0A1S4A526; -.
DR   GeneID; 107793819; -.
DR   OMA; QPNQTPF; -.
DR   OrthoDB; 1532at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   PANTHER; PTHR12276:SF91; CLATHRIN INTERACTOR EPSIN 2-RELATED; 1.
DR   PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT   DOMAIN          1..90
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   REGION          90..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          483..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..209
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        219..240
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..295
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..503
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   867 AA;  91363 MW;  2811E2CF4C8EFA6E CRC64;
     MIMAVIWKRI SDTGKNWRHV YKALTILDYL VASGSERVID EIREHVYQIS TLSDFQYIDS
     SGRDQGSNVR KKSQSLVVLV NDKERIQEVR QKAATNRDKF RNTSVGDMHQ PGSYSSSGGY
     GDRYEEDRYG GRDEERNGYG RDEEKYGRYG DSYSRDGDRY GRGYDERSRD GNKDDDHRGR
     SRSVDDYSYD SRSRSSDRDK NRAYDDDDGQ YSSRGSGARA EDRSQDGSVT DMRLERRFSE
     QNLDAPPSYE EAIGASRSPT HSERNGETPS ASAPKSSSPH SIGSPNQATT PAPAPTAASL
     PTPAPAAASP EKKDIESFDE FDPRASFSVA GAQSNGAMPT TSGGTEVDLL GSLSEPFSSN
     SLALVSATTT TSDVNPFGPT SSEPMFGGAS PAASVPNQMF EDPFGDGPFK AVPTSETVQI
     HPQNIAPPSF LPNSNQSAEV FLSVPQSAEV PSTTYAAPNY AQLELSTSNH DIDILADILP
     PSAPSHSVHP SNDHAIPSGQ LAAQTGFPSD SWLAAQPTGH AASLTGFAAQ PGLQSPQTSF
     PIHGQPVSQI GFSAQTSHSP SFGGYSVPPG QTPQTSFGPQ NGPASLNGFP SASGSFPHPG
     IQVTAGHSMQ TTANFGGYST GLGSTGSVGM QMGQTPTGSS FFAQPATASD IPSQMNFQYS
     QNQTSNLSVP SQSTPVSTAL ISSNQPAKDK FETKSTVWAD TLSRGLVNLN ISGPKTNPLA
     DIGVDFDAIN RKEKRMEKPS TAPVTSTVTM GKAMGSGSGI GRAGAGALRP SSNPMVGSGM
     GMGMGMGAGA PGASAGMGVY GVNQPMGMGM GMGMNRPMNM GMGMNLGQGV HMQQPTGFPP
     GSTMPGGYNP MMGNGNYGQQ SFGGGYQ
//