ID A0A1S4A7B4_TOBAC Unreviewed; 534 AA.
AC A0A1S4A7B4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Mitotic checkpoint serine/threonine-protein kinase BUB1-like {ECO:0000313|RefSeq:XP_016472484.1};
GN Name=LOC107794500 {ECO:0000313|RefSeq:XP_016472484.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016472484.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016472484.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016472484.1; XM_016616998.1.
DR AlphaFoldDB; A0A1S4A7B4; -.
DR SMR; A0A1S4A7B4; -.
DR STRING; 4097.A0A1S4A7B4; -.
DR PaxDb; 4097-A0A1S4A7B4; -.
DR GeneID; 107794500; -.
DR KEGG; nta:107794500; -.
DR OMA; KSPFKRY; -.
DR OrthoDB; 5479089at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IBA:GO_Central.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|RefSeq:XP_016472484.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transferase {ECO:0000313|RefSeq:XP_016472484.1}.
FT DOMAIN 3..171
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 229..531
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 534 AA; 61615 MW; 1F19AD5219AC6CE8 CRC64;
MAVISKNPNN TTSSSSSVDD YLLPWLRSIE KALKERTLTD SNDGRDLHEL CSNCISTFKD
NPRYQNDVRF LKIWFLYMDS SLDHESVYRE IEQNKICLFN SMLYETYALF LEAKGMLTDA
FRIYHLGISR NAEPLGRLKK AQVLFLERMS EKVTAGSLQK MDIVSENGGA CINPWLVSTI
KNLLQKKNPE ILKYDGYHPS KKAYPGKVSL STLQKSARNK TIDIGGYSYQ IKGCAGKGGF
AQVFKACLDG NPDEVVALKI QKPAFPWEFY VYRQLDTRIP ERERLSFGYA HRLHLYSDYS
ILVSDFLANG TLQDAINSNA VIGGSMEEVL CIYYTIEMLC ILQTLHHAQI IHGDFKPDNL
LIRYARDDLT DDVETFRQRT GQWRDQGVCL VDWGRGIDLS LFPEQTEFIG DSRTSGFRCI
EMQEKKPWKF QVDAYGLCVI VHMMLFNSYM EIERRPSPGG GYSYQPKLPF KRYWKVELWR
NLFTKLLNID RAEDHKNMLK SLRESFQDYL CSNPQLIKKL RQLLIKQKAS LCSS
//
