ID   A0A1S4ABJ6_TOBAC        Unreviewed;       840 AA.
AC   A0A1S4ABJ6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Ent-kaur-16-ene synthase, chloroplastic-like isoform X2 {ECO:0000313|RefSeq:XP_016473918.1};
GN   Name=LOC107795749 {ECO:0000313|RefSeq:XP_016473918.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016473918.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016473918.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR   RefSeq; XP_016473918.1; XM_016618432.1.
DR   AlphaFoldDB; A0A1S4ABJ6; -.
DR   GeneID; 107795749; -.
DR   OMA; FACDIRD; -.
DR   OrthoDB; 447330at2759; -.
DR   UniPathway; UPA00213; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
DR   GO; GO:0016102; P:diterpenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00684; Terpene_cyclase_plant_C1; 1.
DR   Gene3D; 1.50.10.160; -; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   Gene3D; 1.50.10.130; Terpene synthase, N-terminal domain; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR044814; Terpene_cyclase_plant_C1.
DR   InterPro; IPR001906; Terpene_synth_N.
DR   InterPro; IPR036965; Terpene_synth_N_sf.
DR   InterPro; IPR005630; Terpene_synthase_metal-bd.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   PANTHER; PTHR31739; ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR31739:SF3; ENT-KAUR-16-ENE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF01397; Terpene_synth; 1.
DR   Pfam; PF03936; Terpene_synth_C; 1.
DR   SFLD; SFLDG01014; Terpene_Cyclase_Like_1_N-term; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT   DOMAIN          274..468
FT                   /note="Terpene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01397"
FT   DOMAIN          544..777
FT                   /note="Terpene synthase metal-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03936"
SQ   SEQUENCE   840 AA;  94894 MW;  33EFD4A181EC8773 CRC64;
     MPLSPATTAT CFTTFSSTNK THRLPPASAS ASASASSYLS VLKPRRFHSL NGTNTVTNKF
     NTASRLGFTL PSHSSACLID STQTAPSTDF ALQSNEATKE RIRELFHKVE ISVSSYDTAW
     VAMVPSPHSA EVPCFPECLD WVLQNQLEDG SWALPHHRPS LLKDVLSSTL ACVLALQKWG
     VGEELISRGL RFIELNFSSA TDEDQYSPIG FDVIFTGMLE YAKELPLKLH LESSVFNELL
     HKRDIELKRL YNSSSLELNP YLAYVSEGMG ELQDWKMVMK YQRKNGSLFN SPSATAASLV
     HLYDSCCLNY LRHALEKFGN AVPAICPIDI HGRLCMVDNL NKLGICRHFA EEIQSVLDET
     YRCWLQGEEE IFTNASTCAM SFRILRVYGY NVSSDPVAQF LEQEHCGGHL KDIYTTLDLY
     QALEMIIATD QPVSKKLNSS LHFLRQRLAS EVYPPSIRMR QIHEQVNDVL KFPSHAKLER
     IANRRNIEHY DIDNTRVLKT SYCSSNFGNK DFLTLAVEDF NFCQSIHRKE LKQLERWLIR
     NRLDKLKFAR EKSAYCYFSA AATIFHPELS DARMSWAKNG VLTTVVDDFF DVGGSMEELN
     NLIQLFKKWD VDISTDCCSE KVGIIFSALH STICEIGDEA FKWQTRSVTR DITDIWSNLL
     NAMLREAEWA RDMSVPTMDE YIANGYVSFA LGPIVLPALY FVGPKLPNDV VQHPEYHSLF
     KLMSTCGRLL NDIRSFERES KDGKLNAVAL SVIHGNGSVS EEAAIGELSR TIEIKRRELL
     NLVLQGEGQG EGSIVPRACK DLFWKMSKVL HHFYIKDDGF SSMGMTDTVK AIIHEPITLE
//