ID A0A1S4ACU3_TOBAC Unreviewed; 431 AA.
AC A0A1S4ACU3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein LOC107796238 {ECO:0000313|RefSeq:XP_016474472.1};
GN Name=LOC107796238 {ECO:0000313|RefSeq:XP_016474472.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016474472.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016474472.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016474472.1; XM_016618986.1.
DR AlphaFoldDB; A0A1S4ACU3; -.
DR SMR; A0A1S4ACU3; -.
DR STRING; 4097.A0A1S4ACU3; -.
DR PaxDb; 4097-A0A1S4ACU3; -.
DR GeneID; 107796238; -.
DR KEGG; nta:107796238; -.
DR OMA; KIEDHAT; -.
DR OrthoDB; 776674at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR46387; POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR46387:SF5; RNASE H DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 28..134
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
FT DOMAIN 138..212
FT /note="Reverse transcriptase RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17917"
FT DOMAIN 248..352
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
SQ SEQUENCE 431 AA; 50491 MW; 1F31B7F5A4B9C2C0 CRC64;
MPVPKKDGKV RMCVDYRDLN RASPKDDFPL PSIYNLIDNY AKQELQSFMD CFITPWEYYY
KMRPFGLKNA KATYMRAITT LFQDMIHKEI EVYVDDGIIK SKTSSDHIAD LRKFLDRLQK
YNLRLNPTKC PYGVPADGAF GCVLGQHDET GRKEQEIYYL SKKFTPYEAQ YSLLEHTCCA
LTWIAQKLRH CFYAYTLYII SRMDLLKYIF QKPILRVSFV REDIDEAYEG WRMFSNGAAN
FKRVVIKAIL VSETDQHYSV SIKLRFPCTN NKVEYEACIL GLSSSIDMNI QGLVVIGDLD
LLIHQVLREW ATKNTMIFLY LYCVQDLIKR FSKIEFKHVP RIQNKFADVL ANLPSMIQHL
DKNFIDPILI EISKQQAYHA LVEEEFDGNP WFPDIKEYLE KGEYRKKCYT HAEAHALEIG
QPLLLERINS V
//
