ID A0A1S4AHZ7_TOBAC Unreviewed; 435 AA.
AC A0A1S4AHZ7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=UDP-glucuronate 4-epimerase 3-like {ECO:0000313|RefSeq:XP_016476048.1};
GN Name=LOC107797658 {ECO:0000313|RefSeq:XP_016476048.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016476048.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016476048.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR RefSeq; XP_016476048.1; XM_016620562.1.
DR AlphaFoldDB; A0A1S4AHZ7; -.
DR SMR; A0A1S4AHZ7; -.
DR STRING; 4097.A0A1S4AHZ7; -.
DR PaxDb; 4097-A0A1S4AHZ7; -.
DR GeneID; 107797658; -.
DR KEGG; nta:107797658; -.
DR OMA; ESFCHAY; -.
DR OrthoDB; 5491077at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR PANTHER; PTHR43574:SF24; NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01370; Epimerase; 1.
DR PRINTS; PR01713; NUCEPIMERASE.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 98..334
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 435 AA; 48129 MW; 20F10674D82B0D39 CRC64;
MSQMKHIDNI PSTPGKYKIE KSPYNRLRLQ FSLTKIIFWS LVFVGLIFVF FYRSPNSVSN
VSSDLSRRSL RTSSYGGPVW EKKIKSSAKI RSKNGICVLV TGAAGFVGTH VSAALKRRGD
GVVGLDNFND YYDPSLKRAR QELLERSGVY IVEGDINDVA LLKKLFEVVA FTHVMHLAAQ
AGVRYAMENP GSYVHSNIAG LVNVLEVCKS VNPQPAIVWA SSSSVYGLNT KVPFSERDRT
DQPASLYAAT KKAGEEIAHT YNHIYGLSIT GLRFFTVYGP WGRPDMAYFF FTRDILKGKS
IPIFEAANHG TVARDFTYID DIVKGCVGAL DTAKKSTGSG GKKKGPAQLR VFNLGNTSPV
PVSDLVSILE KLLKVKAKRL VMKLPRNGDV QFTHANISSA HKELGYKPTT DLQTGLKKFV
RWYLSYYGNG KKSAQ
//
