ID   A0A1S4AUU7_TOBAC        Unreviewed;       604 AA.
AC   A0A1S4AUU7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Flap endonuclease GEN-like 1 isoform X1 {ECO:0000313|RefSeq:XP_016480502.1};
GN   Name=LOC107801655 {ECO:0000313|RefSeq:XP_016480502.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016480502.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016480502.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016480502.1; XM_016625016.1.
DR   AlphaFoldDB; A0A1S4AUU7; -.
DR   STRING; 4097.A0A1S4AUU7; -.
DR   PaxDb; 4097-A0A1S4AUU7; -.
DR   GeneID; 107801655; -.
DR   KEGG; nta:107801655; -.
DR   OMA; CITDSNE; -.
DR   OrthoDB; 26655at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IBA:GO_Central.
DR   GO; GO:0009555; P:pollen development; IBA:GO_Central.
DR   CDD; cd09869; PIN_GEN1; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR11081:SF59; FLAP ENDONUCLEASE GEN-LIKE 1; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SMART; SM00485; XPGN; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|RefSeq:XP_016480502.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT   DOMAIN          1..97
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00485"
FT   DOMAIN          129..199
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          526..604
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..543
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        544..577
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..595
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   604 AA;  68475 MW;  D0272058FCD0B845 CRC64;
     MGVVGNFWEL LKPYGRAEGF DFLRNKRVAV DLSYWIVQQE TAVLKAHIRN PHIRLTFFRT
     INLFSKFGAF PVFVADGTAS PLKSQARIAR FFRASGIKLS SLPAAEEGIS IERNKAFQKC
     EQECVELLEL LGVPVLKAKG EAEALCAQLN QEGQVDACIT ADSDAFLFGA KCVIKNIQPN
     SKEPLEFYHM SDIESGLGLR RNHLIAISLL VGDDHNLIGV PGIGLETALR FVKSFSEDEI
     LSRLQEIGRG DVQVLQRDVN LDCNYIPGSD ESPWKTKVQH CSFCGHPGSK KAHHKFACQD
     CSSTANEGCI QKPSGFKCNC SSCDLDNKEK EQKRNENWQI KVCRMIASEQ NFPNNEITEM
     YLNKHQQSAD GDYHLTWSSP KTDMLVDYLA YYQHWEPSYT RQRMLPMLST IFLRDVASNS
     KDQLLCGQYE FDSIQRVKTR FGHQLYVINW KKTTREMSNE ICIPSENPDM EQELRIADDG
     SKDLLDEPEV LQIHIKDGCS FLSTEEDMEL VQSAFPEKVS QFLRDKELKE TKSSRKRSVK
     PENSESPRGV QPSITNFYRS SKVQATPGEN ESRSSKISAD TSGERDKEPI RNYSKSARRK
     LLFG
//