ID   A0A1S4B017_TOBAC        Unreviewed;       708 AA.
AC   A0A1S4B017;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Cyclic nucleotide-gated ion channel 1-like {ECO:0000313|RefSeq:XP_016482166.1};
GN   Name=LOC107803078 {ECO:0000313|RefSeq:XP_016482166.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016482166.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016482166.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the cyclic nucleotide-gated cation channel (TC
CC       1.A.1.5) family. {ECO:0000256|ARBA:ARBA00010486}.
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DR   RefSeq; XP_016482166.1; XM_016626680.1.
DR   AlphaFoldDB; A0A1S4B017; -.
DR   STRING; 4097.A0A1S4B017; -.
DR   PaxDb; 4097-A0A1S4B017; -.
DR   GeneID; 107803078; -.
DR   KEGG; nta:107803078; -.
DR   OMA; CWRDVCS; -.
DR   OrthoDB; 3076617at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR45651:SF79; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 1-LIKE; 1.
DR   PANTHER; PTHR45651; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        371..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          479..563
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
SQ   SEQUENCE   708 AA;  80930 MW;  CCBB8093E1BFD3E1 CRC64;
     MNHRQAEFVR FQDWKSEKSS EGNFHAKGGV HRSKVVIASN ELHNGLESGK WRAKGIIQAV
     KSSLSGFVEE SLGSKKNILD PQGPFLQKWN KIFVLSCVIA ISLDPLFLYI PVIDNDNKCL
     GLDRTLEVTA SVLRSFTDIF YFLHIALQFR TGFIAPSSRV FGRGVLIEDA WEIAKRYLST
     YFLIDILAVL PLPQVVILII IPKLRGSRSL NTKNLLKSVV FFQYIPRVLR VYPLYKEVTR
     TSGILTETAW AGAAFNLFLY MLASHVLGAF WYLFSIERET TCWKQACGNS SPCHHASLYC
     DDDHTKFKTL LNSSCPIETP NATLFDFGIF LDALQSGVVG PMDFPQKFFY CFWWGLQNLS
     SLGQNLQTST FIWEICFAVF ISIAGLVLFA FLIGNMQTCL QSSTLRLEEM RVKRRDAEQW
     MSHRLLPENL RERIRHYEQY RWQETRGVDE ENLIHNLPKD LRRDIKRHLC LALLMRVPMF
     EKMDEQLLDA LCDHLKPVLF TKDSFIVREG DPVDAMLFVM RGKLLSVTTN GGRTGFFNSE
     HLKAGDFCGE ELLTWALDPN SSTNLPISTR TAQALSEVEA FALVADDLKL VASQFRRLHS
     KQLRHTFRFY SGQWRTWAAC FIQAAWRSYC RKKVEESLRE EENRLQDALA NEGGSSPSLG
     ATFYASRFAA NALRALRRNT AKKARVPDRI SPILLQKPTE PDFTAEDK
//