ID   A0A1S4B0U0_TOBAC        Unreviewed;       766 AA.
AC   A0A1S4B0U0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Probable apyrase 7 {ECO:0000313|RefSeq:XP_016482555.1};
GN   Name=LOC107803368 {ECO:0000313|RefSeq:XP_016482555.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016482555.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016482555.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC       {ECO:0000256|ARBA:ARBA00009283}.
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DR   RefSeq; XP_016482555.1; XM_016627069.1.
DR   AlphaFoldDB; A0A1S4B0U0; -.
DR   SMR; A0A1S4B0U0; -.
DR   STRING; 4097.A0A1S4B0U0; -.
DR   PaxDb; 4097-A0A1S4B0U0; -.
DR   GeneID; 107803368; -.
DR   KEGG; nta:107803368; -.
DR   OMA; PEYYVIL; -.
DR   OrthoDB; 1222189at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IBA:GO_Central.
DR   GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR11782:SF125; APYRASE 7-RELATED; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        117..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        601..621
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          729..766
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        289
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT   BINDING         320..324
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ   SEQUENCE   766 AA;  84866 MW;  8593A65E5789FD4D CRC64;
     MVLNKVTEIV SAAVARFSNP KTSSTPYPSS GLPPLPGSLN ISSLDQKNKL RLSSSLQDLS
     AYRRLDLEDG DLNPEIERGS TNLKRLNLFK RENLGTSFSK VKGSPAVNSA RTKWKRVILV
     LLCLLLVAFL LYMLFFYLNL FRGESKFYVV LDCGSTGTRV YVYQSSPNYK KDSDLPIVLR
     SLPEGFQRNS RLQSGRAYNR METEPGFDKL VHNTSGLRKA IKPLIKWAVK QIPKHAHKST
     YLYLYATAGV RRLPNSDSEW LLNNAWSILK SSPFMCKREW VKTITGMEEA YYGWIAMNYH
     TGILGAKPKK GTFGALDLGG SSLQVTFESK ENLPDETSLE LNIGAVNHHL TAYSLAGYGL
     NDAFDKSVVQ LLKRLPKISN ADLTSGNIEI KHPCLNSGYK EQYICTHCVS LYQEGGNPTT
     GREVSGKGGK PGVRVQLVGA PKWEECNSLA KVAVNLSEWS GKNPGIDCEL QPCALAENLP
     RPYGQFYAMS GFYVVYRFFN LTPDAALDDV LEKGQEFCEK TWDVAKTSVA PQPFIEQYCF
     RAPYVVFLLR EGLHITDSQV TIGSGSITWT LGVALLEAGK AVSTGVELIS YKLLLMKMHP
     IILFAILFAS LAVLLCALSC VGKWMPRFFR RQYLPLFGNN SASSTSIINI PAPFSFRRWS
     PVITGEGRVK MPLSPTVANT QQRPFDTGHG FGGNGIQLTE SSLYSSSSSV AHSFSSGSLG
     QMQFESSSTG SFWSPHRSQQ RLQSRRSQSR EDLISSLAEV PLPPKV
//