ID A0A1S4B1X2_TOBAC Unreviewed; 446 AA.
AC A0A1S4B1X2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=COP9 signalosome complex subunit 2 {ECO:0000256|ARBA:ARBA00014879};
GN Name=LOC107803597 {ECO:0000313|RefSeq:XP_016482831.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016482831.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016482831.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN2 family.
CC {ECO:0000256|ARBA:ARBA00009318}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016482831.1; XM_016627345.1.
DR STRING; 4097.A0A1S4B1X2; -.
DR PaxDb; 4097-A0A1S4B1X2; -.
DR GeneID; 107803597; -.
DR KEGG; nta:107803597; -.
DR OMA; WMLAYNE; -.
DR OrthoDB; 5477605at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0008180; C:COP9 signalosome; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000338; P:protein deneddylation; IBA:GO_Central.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10678; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR10678:SF3; COP9 SIGNALOSOME COMPLEX SUBUNIT 2; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00753; PAM; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 243..419
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 52165 MW; 59D878ED7212A384 CRC64;
MGSDADMEDY GFEYSDEEPE EQDVDIENQY YNSKGLVETE PEAALEGFAE VVRMEPEKAE
WGFKALKQTV KLYYKLGKYK EMMDAYREML TYIKSAVTRN YSEKCINNIM DFVSGSASQN
FSLLQEFYET TLKALEEAKN ERLWFKTNLK LCKIWFDIGE YGRMSKILKE LHKSCQKEDG
TDDQKKGTQL LEVYAIEIQM YTETKNNKKL KELYNKALSV KSAIPHPRIM GIIRECGGKM
HMAERQWAEA ATDFFEAFKN YDEAGNQRRI QCLKYLVLAN MLMESEVNPF DGQEAKPYKN
DPEILAMTNL IAAYQRNEIL EFEKILKSNR RTIMDDPFIR NYIEDLXKMI NHVVLYHELL
LLSSACNRIP YWLLLFDMQE LNVPEKDVEE LLVSLILDNR IHGHIDQVNR LLECGDRSKG
MKKYAAIDKW NTQLKSLYQT VGNRVC
//
