ID A0A1S4BD74_TOBAC Unreviewed; 1000 AA.
AC A0A1S4BD74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC107807003 {ECO:0000313|RefSeq:XP_016486766.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016486766.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016486766.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016486766.1; XM_016631280.1.
DR AlphaFoldDB; A0A1S4BD74; -.
DR SMR; A0A1S4BD74; -.
DR PaxDb; 4097-A0A1S4BD74; -.
DR GeneID; 107807003; -.
DR KEGG; nta:107807003; -.
DR OMA; FCTNDRE; -.
DR OrthoDB; 1203965at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0006952; P:defense response; IEA:UniProt.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF38; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|RefSeq:XP_016486766.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|RefSeq:XP_016486766.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|RefSeq:XP_016486766.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 639..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 690..964
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1000 AA; 110280 MW; B478F14C59560599 CRC64;
MKNFQENMVP LIHIVTLFTI LGTSFSSSSD FLALVSLKQG FGFSNPALSS WDTSNPSSVC
SWAGIKCSQG RVVSINLSNM DLYGSVSPAI SSLDKLVELS IDGNNFTGEI KIDNMSSLQS
VNISNNIFSG NLDWNYSSLS NLEILDAYNN NFSSFLPLGV VNLKKIKYLD LGGNYFYGRI
PESYGDLIEL EYLSLAGNDL HGRIPKALGN LTNLKEIYLG YFNVFVGGIP KEFGKLENLV
HMDISSCELD GPIPPELGNL KLLNTLFLHI NLLSGQIPKE LGNLTGLVNL DLSANALTGE
IPFELINLQQ LRLFNLFMNK LHGSIPDFIA DFPELKILGL WMNNFTGVIP EKLGQNGKLQ
ELDLSSNKLT GTIPKDLCAS KQLRILILLK NFLFGPIPED FGTCSSLVRV RLGQNYLNGS
IPYGFIYMPE LNLVELHNNY LSGTLSENSN ISSKPAKLGQ LNLSNNQLYG SLPFSLSNFT
SLQILSLGGN QFSGPIPHTI GQLSQALKID LNHNFLSGEI PPEIGNCVHL TYLDLSQNNF
SGSIQPRLSE IRILNYLNLS RNHLNETIPK SIGTMRSLTT ADFSFNDLSG KLPESGQFAY
FNATSFAGNP RLCGSLLNNP CNFTLITDPP VKSRGDFKLI FALGLLICSL VFAAAAIIKA
KSFKKTGLNS WKMTAFQKVE FSVADVLECV KDGNVIGRGG AGIVYHGKMP NGVEIAVKKL
LGIGNNSHDH GFRAEIRTLG NIRHRNIVRL VAFCSNKETN LLVYEYMRNG SLGEALHGKK
GGFLSWNLRY KIAIEAAKGL CYLHHDCSPL IVHRDVKSNN ILLNSNFEAH VADFGLAKFL
VDGGASECMS AIAGSYGYIA PEYAYTLRVD EKSDVYSFGV VLLELITGRR PVGEFGDGVD
IVQWSKRVTN CKREQVTHIV DPRLTTVPED EAMHLFFVAM LCIQENSVER PTMREVIQML
SEFPRQSPEY QPSSSSVVFQ KVKSLENDQS CPKIRKELLV
//
