ID A0A1S4BIS4_TOBAC Unreviewed; 325 AA.
AC A0A1S4BIS4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Homeobox protein knotted-1-like 1 {ECO:0000313|RefSeq:XP_016488739.1, ECO:0000313|RefSeq:XP_016488740.1};
GN Name=LOC107808713 {ECO:0000313|RefSeq:XP_016488739.1,
GN ECO:0000313|RefSeq:XP_016488740.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016488739.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016488739.1, ECO:0000313|RefSeq:XP_016488740.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC {ECO:0000256|PROSITE-ProRule:PRU00559}.
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DR RefSeq; XP_016488739.1; XM_016633253.1.
DR RefSeq; XP_016488740.1; XM_016633254.1.
DR STRING; 4097.A0A1S4BIS4; -.
DR PaxDb; 4097-A0A1S4BIS4; -.
DR GeneID; 107808713; -.
DR KEGG; nta:107808713; -.
DR OMA; STHYRWP; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR005540; KNOX1.
DR InterPro; IPR005541; KNOX2.
DR PANTHER; PTHR11850:SF355; HOMEOBOX PROTEIN KNOTTED-1-LIKE 1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF03789; ELK; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF03790; KNOX1; 1.
DR Pfam; PF03791; KNOX2; 1.
DR SMART; SM01188; ELK; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM01255; KNOX1; 1.
DR SMART; SM01256; KNOX2; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51213; ELK; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 208..228
FT /note="ELK"
FT /evidence="ECO:0000259|PROSITE:PS51213"
FT DOMAIN 228..291
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 229..292
FT /note="Homeobox; TALE-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 165..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36413 MW; 5D2C374BBB75974E CRC64;
MMDELSKLHS AIACSSNNNH VVGVLEHITG QQQEGPINNS SVDNNLEKAS LEMSDLIKAQ
IANHPLYPNL LSAYLQCRKV GAPQEMASIL EEISKENHLI SSGHNTEIGT DPELDEFMES
YCAVLLKYKE ELSKPFDEAT TFLNNIESQL SSLCKENLTT TTTTSFNSNN NYLSDEAGGT
SDEDLCCGEM EAADSTQESP ANREGDNELK ETLMRKYSGY LSSLRKEFLK KRKKGKLPKD
ARTALLEWWN THYRWPYPTE EEKNRLSEIT GLDPKQINNW FINQRKRHWR PSEDMKYALM
EGVSSGSIAG SMYFDGAGGT GSIGT
//
