ID A0A1S4BLR4_TOBAC Unreviewed; 492 AA.
AC A0A1S4BLR4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=AAA-ATPase At2g46620-like {ECO:0000313|RefSeq:XP_016489800.1};
GN Name=LOC107809663 {ECO:0000313|RefSeq:XP_016489800.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016489800.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016489800.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the AAA ATPase family. BCS1 subfamily.
CC {ECO:0000256|ARBA:ARBA00007448}.
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DR RefSeq; XP_016489800.1; XM_016634314.1.
DR AlphaFoldDB; A0A1S4BLR4; -.
DR SMR; A0A1S4BLR4; -.
DR STRING; 4097.A0A1S4BLR4; -.
DR PaxDb; 4097-A0A1S4BLR4; -.
DR GeneID; 107809663; -.
DR KEGG; nta:107809663; -.
DR OMA; YAVRRLW; -.
DR OrthoDB; 819832at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006950; P:response to stress; IEA:UniProt.
DR Gene3D; 6.10.280.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025753; AAA_N_dom.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23070:SF176; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23070; BCS1 AAA-TYPE ATPASE; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF14363; AAA_assoc; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 228..353
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 417..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 56220 MW; B58A826ED3F63DCA CRC64;
MWIVNIFFLL FLVPCFLFLV RFILYRTALI FVLRKWANWV DDRIHVHQYL KVAELNENGQ
DNQFYRRVSL YVNSLPSVED SNFTNLFSGK KSTDIVLSLD DNQVIQDEFL GARISWVNKV
ERFNNGVCNR SFLLRIKKKD KRRILPPYFQ HIHTVSDDIE QRRRELKLFI NNGPSENPIK
GRWRSVPFTH PATLDTIAMD TDLKIKVKSD LETFTKSQNY YHKMGRAWKR NYLLYGPSGT
GKSSFIGAMA NFLNYDVYDV DLSRVSDDSD LKLLLLQTTS RSLIVIEDLD RSINEKLITT
SFSGLLNFMD GIVNSCCGDE KIMVFTMNSK EHIDPAMLRP GRIDVHIHFP LCDFNSFRSL
ANNYLGVKEH KLFPQVEEIF QSGATMSPAA IGELMMVNRS SPSRALKSVI TALQSNGTEG
KIAGRGKRLS DSASSPGLPF PSPSPQAEET GGVNWKDSVP VAKEFRKLYG LLRLKSCKKP
GSFDHDSEMI ER
//
