ID A0A1S4BLX4_TOBAC Unreviewed; 1778 AA.
AC A0A1S4BLX4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4G-like {ECO:0000313|RefSeq:XP_016489870.1};
GN Name=LOC107809718 {ECO:0000313|RefSeq:XP_016489870.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016489870.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016489870.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR RefSeq; XP_016489870.1; XM_016634384.1.
DR SMR; A0A1S4BLX4; -.
DR STRING; 4097.A0A1S4BLX4; -.
DR PaxDb; 4097-A0A1S4BLX4; -.
DR GeneID; 107809718; -.
DR KEGG; nta:107809718; -.
DR OrthoDB; 92033at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016281; C:eukaryotic translation initiation factor 4F complex; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR Gene3D; 1.25.40.180; -; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF55; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G-LIKE; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|RefSeq:XP_016489870.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 1600..1723
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1233..1258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1366..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..590
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..811
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1038..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1366..1391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1392..1409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1429..1444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1518..1538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1778 AA; 195174 MW; 29D17F23ED880142 CRC64;
MQRRGDQKKS ESQTNYRRNS SRLSGRSGSA QPQYQRVTSG KGGGSSVLPP PSPDSSVSSS
PTTPSFKKSD GETGSLKVTD AIADQESVDL QNDAPTRISG SDKFIEPTDT VRHDEYQMVS
SDLSSQHASI NLDQSAPKTP MKDDTSKKVS LQFGSFTPGF VNGMQIPQRT SSAPPNMDEQ
KRHQARSSPF RPLQLLSSSA LHQPQLREDI GKPTNKTPDP QHFPERDLPV HVSPAHPVSN
MQKLSSLPFP GVPVNPPFMQ PHGPVHFGVP GAQVQHQGMP CSSFPMPMPL PVGNPNIRHP
PFVPGLQPHH MQLQGAMHQG QMMNFPPKFG HQLSSQFGST GFGISPQFGQ HVRNVNPRRS
VKITHPDTKE ELRLDEKVDM RLDGGSSGLA IHHLGGLPSQ PMHYGPSRPI NFFPHVQPSP
IFLQNPTSVP ITNSLVAPCA PALGYNSPAS VHVAVNQAPG SVGREILTSS FPIAKKTTEK
EKAQQPALRA SSNEEEPKIL SETSVEVSES ASKPTPFASP SDKSLVSVDR PPSSGATYVE
SNINHVRGVS DIETELKNPP NKSQLHPQQQ REAGNPTSIS NPSPPNSVDR ISECQNAETI
ETQATSTLSK TLGDASICSG ASQRNADEAS EQSGVTIDEG NVIAGKGIRQ GQLTTNPFGR
PSLGIKNEDT YSSMTAKASE QTERNSHLAT ENGRNASDQL SSAGGCETNN VVYKLSHSAA
LSGRNISDVM VPGCGSPKYL TEDNELGSIS PETRPAAKTN NKDVLLSGSG AKHHEDSHIP
TSPSSPSYTK TRGKVSEETK TEYRRVQGSG SKDKPSNKVK STTSRGKKKR REILQKADAA
GDTLDLYMAF KGPKEKQQSS VSSESVESCT SLTARKISSS SNEEDFSANE DKKSTGEPNN
WEDAAMSTPK LENSGNNKIV NDMLRHPNGG SATTGKMRYS RDFLLTLSSH FADLPANFEV
PWHMVEALLS PNASISKGVD FNKNDPNSCP GQTNTRRQGS SSWTESCPGQ TNTSRQGSSS
WTEHRPTGMA DDSRWVNEQY IDINQGGSAN GPRSGRGNHK NMRNLQGQPP SQYVSVFPAG
AMLPLASHGG VQHIRSDANR WQRVSGSRKG LMPSPHSPLQ VMHKADKKYE IRKVTDEEEA
KRRQLKAILN KLTPQNFEKL FEQVKEVNID SANTLAGVIS QIFDKALMEP TFCEMYANFC
SHLAGELPDF VEDDQKITFK RLLLDKCQEE FERGEREEAE ADSMEEDGEM KMSEGKREEK
RLQARRRMLG NIRLIGELYK KKMLTERIMH ECIQKLLGQY QTPDEEDIEA LCKLMSTIGD
MIDHSKAKDY MDAYFDMMTT MANNTDLSSR VRFMLMDIID LRKNKWQQRR KVEGPKKIEE
VRRDAVQERR AQVTRSTRGP STVSSSRRGQ PADLGPRPSM FSPPAPQMTP FRGMTSQNRG
FGNQDFRSES RHPHESRTSS AALPQRPVDD KTMSLGPRGS PGRATSFRGP PMHSGGPVAD
VHAGFGESRR PAAGSGGRNP TSGWSPYNSR QESTSKYAPG TAVKPIAYAQ PNQREHEHYA
EREVTNINPS GRSAEPPAAA HPHRPSAVSN SPGMIWSEER LREMSIGAIR EFYSAVDEDE
VVLRIRELNS SSFLPMMLSI WVNDSFQRKE RDRDLLARLL ISLTKSKVVP DISQLIEGFE
SVLATLEDEV TDAPKAPTFL GHIFGRLISE NVISLKEAGH LIRHAGEEPG HLLQTGLGYE
VLESTFNRIR SEKGESALRD ICSASSTQLE DFRPPELS
//
