ID A0A1S4BNY3_TOBAC Unreviewed; 1436 AA.
AC A0A1S4BNY3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Fanconi anemia group I protein isoform X2 {ECO:0000313|RefSeq:XP_016490565.1};
GN Name=LOC107810317 {ECO:0000313|RefSeq:XP_016490565.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016490565.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016490565.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016490565.1; XM_016635079.1.
DR GeneID; 107810317; -.
DR OMA; QSMRMMN; -.
DR OrthoDB; 1210920at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026171; FANCI.
DR InterPro; IPR029310; FANCI_HD1.
DR InterPro; IPR029312; FANCI_HD2.
DR InterPro; IPR029308; FANCI_S1.
DR InterPro; IPR029315; FANCI_S2.
DR InterPro; IPR029314; FANCI_S4.
DR PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR Pfam; PF14679; FANCI_HD1; 1.
DR Pfam; PF14680; FANCI_HD2; 1.
DR Pfam; PF14675; FANCI_S1; 1.
DR Pfam; PF14676; FANCI_S2; 1.
DR Pfam; PF14678; FANCI_S4; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 100..269
FT /note="FANCI solenoid 1"
FT /evidence="ECO:0000259|Pfam:PF14675"
FT DOMAIN 293..374
FT /note="FANCI helical"
FT /evidence="ECO:0000259|Pfam:PF14679"
FT DOMAIN 387..540
FT /note="FANCI solenoid 2"
FT /evidence="ECO:0000259|Pfam:PF14676"
FT DOMAIN 559..793
FT /note="FANCI helical"
FT /evidence="ECO:0000259|Pfam:PF14680"
FT DOMAIN 1099..1337
FT /note="FANCI solenoid 4"
FT /evidence="ECO:0000259|Pfam:PF14678"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1336..1436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1351..1365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1366..1391
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1412..1436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1436 AA; 160930 MW; 04C4E52BC4A4998E CRC64;
MTSAATKNPS AVRHHQPPPP PSLTDVDIVQ LAQLYHPQSS TPLPQFLLSD DSHQTLVSYL
HSRASSPNPS LAVSEYLSAL LSLTQLHASL SPLVPLLLSS YISLFTSHKI LHDKSSLSIF
QLFVSHIETV QVHELTTIVD LIISYLPQII DSEDTHVLTI LAKCIELIRF SNDVDKPLEY
VDKVFDKILS CDWSKVLLLK LVEIVKDLNF IEKGKRREFL ERVFSGMRNV DLQDLPGLVY
QLLILGSKGF GKKEVVEGIV MYFGGVKSGG SIMRQVEGTV LLHVNFAVKQ DPSLGQEVLG
LVRSDYRVFN HFTVAILLSV ARVKRLADSS IAVLKTSLFA AYKDLKFARS CKWLSSDLKE
HYLHTARNME KAVLRAVSES NCGREHVVPS TVQLGFVLLE GIEEGTKKYE KSDDMIGPDE
LGTQVLKSLF EVHDMARNEI IEQCKLRILS LKPEQSFPVI RLLGCLICTY PYPMLEHISH
LKELLDYFTF MNEKVSSHLV AALLPLIRSS RDLQDYTILV LRKAMFRRED SIRLAATSSI
VNLILAEKQS KKDGPFSCQD SSSQASSSQQ AEVYRALGSS LFQELNGLLQ RCLYQQAKVR
EILYHGLLKL VLVDPLTSGA VFDFLFPHFL RFYREDADVL LDINQCTNSE SGKVYIQEPL
DCLLSCISWM LLLQPHGKTD HPSDSWTCFG FSLTQENEPG KAWSKESLSN ALSKIRDFLR
NADMEGLLGK NQDTGSTPLE EEKRRCCSSI LLGIIEVMLN VVGTEFGKTT DVKKFELEKE
LFDFIGIFES LDRNICRQGG GSTQRGFIRP TASTTSEELE FSGSKLCHER IPLLATSIIY
QLLQNTIESW RYDGFNNNVA SQKHSQLSSG KAPTQYYKIL SFTLNLCLRQ LKASSVVRQQ
DPLKMLIYGE IKQLGSPLLK MIWWLLSEPK SMTDSRKKDA NVKKDLDDRK EYIHSALLSL
KELLALILHE LDYSVLIDDL AAVSGPGDEV GNAMDGDIDT ECEKADDILY KYTSEELFIK
NSIRPLISML LARSFFREVE VLCDIIMLIS NKLPEEQRNL VGNWAKCICK TSKISNPKAA
KSIVSIAMLL TSPPSDLIIA EDMAAELLKV VGSESEKFDS QVTLDAYSVI NKSTSAAVAS
LILHLVESVI LDTEWVIRKL KIYSVANTRA VLVNQNGERD PGLALEEIVY SRAEAVVKVL
SSFVMMDLKD PQAEQLVKLA ARFYKNLAQM SKLLIASKGV KQPLPSLKYQ KLVEVTCSQL
TAPLYNFMVV MQKKQLESTK SKALVNKIKR ENRCIPDLIY QIEDYEKYLI QISKATKINL
LRHAKRSTSR DFKIIEPQSF SVEEGAGSQD AEDNDAARGE NEEDPRDEEG NGAEDESVVG
AEDDDEGNEV EDALMAAYNS PPAVEASESE NEAEADLPKA KRAKMTRVVE DSDEEA
//
