ID A0A1S4BQ19_TOBAC Unreviewed; 264 AA.
AC A0A1S4BQ19;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Trans-resveratrol di-O-methyltransferase-like {ECO:0000313|RefSeq:XP_016490961.1};
GN Name=LOC107810676 {ECO:0000313|RefSeq:XP_016490961.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016490961.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016490961.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-independent O-methyltransferase family. COMT
CC subfamily. {ECO:0000256|ARBA:ARBA00034481}.
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DR RefSeq; XP_016490961.1; XM_016635475.1.
DR AlphaFoldDB; A0A1S4BQ19; -.
DR SMR; A0A1S4BQ19; -.
DR STRING; 4097.A0A1S4BQ19; -.
DR PaxDb; 4097-A0A1S4BQ19; -.
DR GeneID; 107810676; -.
DR KEGG; nta:107810676; -.
DR OMA; WIMHDWK; -.
DR OrthoDB; 5230501at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0008171; F:O-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IBA:GO_Central.
DR GO; GO:0019438; P:aromatic compound biosynthetic process; IBA:GO_Central.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IBA:GO_Central.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746:SF290; TRANS-RESVERATROL DI-O-METHYLTRANSFERASE-LIKE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 33..80
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 132..260
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 264 AA; 29189 MW; 89AD2CBB4FC34C3A CRC64;
MALSNNIRDK TREILAAQAH IANHVFNYIN FVSLKCTIQL EIPDIIHNHG KPMTLSNLVN
ALPINKAKGQ DCIYRLMRIL IHSGFFIQTK INENEEEGYL LTPNSHLLLK NEPLSLAPFV
LAQLDPILMD PFQSLSKWLQ NSDSTPFATA HGKPLFEYAG DEPRLNYLFN EAMASDARLM
ISVVIKNGRG IFEGLKSLAD VGGGIGTVAK AISNAFPEIK CTVFDLPHVV EGLEGSNKLS
YVGGDMFKSV PSADAILLKE KYYS
//
