ID A0A1S4C130_TOBAC Unreviewed; 283 AA.
AC A0A1S4C130;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Aquaporin PIP2-13s {ECO:0000313|EMBL:DAC84314.1};
DE SubName: Full=Aquaporin PIP2-2-like {ECO:0000313|RefSeq:XP_016494749.1};
GN Name=LOC107813938 {ECO:0000313|RefSeq:XP_016494749.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016494749.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|EMBL:DAC84314.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=32517797;
RA De Rosa A., Watson-Lazowski A., Evans J.R., Groszmann M.;
RT "Genome-wide identification and characterisation of Aquaporins in Nicotiana
RT tabacum and their relationships with other Solanaceae species.";
RL BMC Plant Biol. 20:0-266(2020).
RN [3] {ECO:0000313|RefSeq:XP_016494749.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BK011419; DAC84314.1; -; mRNA.
DR RefSeq; XP_016494749.1; XM_016639263.1.
DR STRING; 4097.A0A1S4C130; -.
DR PaxDb; 4097-A0A1S4C130; -.
DR GeneID; 107813938; -.
DR KEGG; nta:107813938; -.
DR OMA; LMDPHEL; -.
DR OrthoDB; 3236018at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR NCBIfam; TIGR00861; MIP; 1.
DR PANTHER; PTHR45687; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR45687:SF98; AQUAPORIN PIP2 10; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 283 AA; 30323 MW; C5D289DB1CB43CEA CRC64;
MAKNVGSEGS FTTKDYQDPP PAPLIDPEEL TQWSFYRALI AEFIATLLFL YITVLTVIGY
KSQSATATDP CAGVGILGIA WAFGGMIFVL VYCTAGISGG HINPAVTFGL FLARKVSLIR
AVMYMVAQCL GAICGVGLVK AFQSAYYHRY DGGANMLSDD YSHGVGLSAE IIGTFVLVYT
VFSATDPKRN ARDSHVPVLA PLPIGFAVFM VHLATIPITG TGINPARSLG AAVIFNQHKA
WKDHWIFWVG PFIGAAIAAF YHQFILRAGA AKALGSFRSS SQV
//
