ID A0A1S4C6G7_TOBAC Unreviewed; 631 AA.
AC A0A1S4C6G7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Clathrin assembly protein At2g25430 isoform X4 {ECO:0000313|RefSeq:XP_016496718.1};
GN Name=LOC107815618 {ECO:0000313|RefSeq:XP_016496718.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016496718.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016496718.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
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DR RefSeq; XP_016496718.1; XM_016641232.1.
DR AlphaFoldDB; A0A1S4C6G7; -.
DR GeneID; 107815618; -.
DR OMA; ILIAMYP; -.
DR OrthoDB; 3667239at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR CDD; cd16987; ANTH_N_AP180_plant; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR048050; ANTH_N_plant.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951:SF13; ASSEMBLY PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 24..160
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 354..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..404
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 69448 MW; DBBB614180488D43 CRC64;
MATTTIRKAI GAVKDQTSIG IAKVASNMAP ELEVAIVKAT SHDDEPAGEK YVREILQLTS
YSRGYVSACM SAISKRLGKT RDWIVALKCL MLIHRLLNDG DAVFQQEIMY ATRRGTRLLN
LSDFKDEAHS NSWDHSAFVR TYALYLDQRL ELMVFERKQN GSTGGEIERY GSREEHFRSP
PSSNRGHEYD FGEFRDEPGY GMRRSRSSGD VRESIQENKE VTPLREMKPE RILGKMTHLQ
RLLDRFLSCR PTGLAKNERM VLVALYPMVK ESFKIHTDIC DVLALLLDKF FDMEFEDCVK
AFDAYASAAK QIDELVGFYD WCKDIGVTRS SEYPEVARIT SKLLDTLQEF VRDRAKATKS
PERKVESQST PQEQEPAPDM NEIKALPPPE DYTPPPPPEP ELPKPVVQET GDLVDLREEG
VTADDQGNKL ALALFAGSGT SNANGSWEAF PSNGETEVTS AWQNPAAESG KADWELALVE
TASNLSKQKA ALGGGLDPLL LNGMYDQGVV RQHVATAQSS GGSASSVALP GLGKSATPVL
ALPAPDGTVQ TVGQDPFAAS LSVPPPSYVQ MADLQKKEQL LAQEQMVWQQ YARDGMQGQM
SLAKISTGGY YDPGQPPAMS YAMPPVNGAG F
//
