ID A0A1S4CHP1_TOBAC Unreviewed; 444 AA.
AC A0A1S4CHP1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=26S proteasome regulatory subunit 4 homolog A-like {ECO:0000313|RefSeq:XP_016433828.1, ECO:0000313|RefSeq:XP_016500720.1};
GN Name=LOC107819147 {ECO:0000313|RefSeq:XP_016500720.1};
GN Synonyms=LOC107760308 {ECO:0000313|RefSeq:XP_016433828.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016500720.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016433828.1, ECO:0000313|RefSeq:XP_016500720.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR RefSeq; XP_016433828.1; XM_016578342.1.
DR RefSeq; XP_016500720.1; XM_016645234.1.
DR STRING; 4097.A0A1S4CHP1; -.
DR PaxDb; 4097-A0A1S4CHP1; -.
DR GeneID; 107760308; -.
DR GeneID; 107819147; -.
DR KEGG; nta:107760308; -.
DR KEGG; nta:107819147; -.
DR OMA; QDDTDPM; -.
DR OrthoDB; 1707207at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0036402; F:proteasome-activating activity; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF154; 26S PROTEASOME REGULATORY SUBUNIT 4 HOMOLOG A-LIKE; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942,
KW ECO:0000313|RefSeq:XP_016433828.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 222..361
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 49456 MW; F859D47474B84127 CRC64;
MGQGTPGGLN RQLPGDRKND GDKKEKKFEP AAPPARVGRK QRKQKGSEAA ARLPTVTPLT
KCKLRLLKLE RIKDYLLMEE EFVANQERLK PQEEKTEEDR SKVDDLRGSP MSVGNLEELI
DENHAIVSSS VGPEYYVGIL SFVDKDQLEP GCAILMHNKV LSVVGLLQDD VDPMVSVMKV
EKAPLESYAD IGGLDAQIQE IKEAVELPLT HPELYEDIGI KPPKGVILYG EPGTGKTLLA
KAVANSTSAT FLRVVGSELI QKYLGDGPKL VRELFRVADD LSPSIVFIDE IDAVGTKRYD
AHSGGEREIQ RTMLELLNQL DGFDSRGDVK VILATNKIES LDPALLRPGR IDRKIEFPLP
DIKTRRRIFQ IHTARMTLAD DVNLEEFVMT KDEFSGADIK AICTEAGLLA LRERRMKVTH
ADFKKAKDKV MFKKKEGVPE GLYM
//
