ID A0A1S4CK79_TOBAC Unreviewed; 592 AA.
AC A0A1S4CK79;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Chloride channel protein CLC-c-like {ECO:0000313|RefSeq:XP_016501637.1};
GN Name=LOC107819951 {ECO:0000313|RefSeq:XP_016501637.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016501637.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016501637.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_016501637.1; XM_016646151.1.
DR AlphaFoldDB; A0A1S4CK79; -.
DR SMR; A0A1S4CK79; -.
DR STRING; 4097.A0A1S4CK79; -.
DR PaxDb; 4097-A0A1S4CK79; -.
DR GeneID; 107819951; -.
DR KEGG; nta:107819951; -.
DR OMA; FTHEHIV; -.
DR OrthoDB; 315083at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002251; Cl_channel_pln.
DR PANTHER; PTHR11689:SF144; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01120; CLCHANNELPLT.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 85..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 592
FT /evidence="ECO:0000313|RefSeq:XP_016501637.1"
SQ SEQUENCE 592 AA; 64219 MW; F0E6DA2CFEB8F94F CRC64;
MENQVDIENE GGMVEEEKID LERNFSTISE SGIREPLLKS KSRVNNTSQI AIVGANVYPI
ESLDYEIVEN DLFKQDWRSR KKVQIFQYIF LKWTLVLLIG LSTGLVGFFN NIGVENIAGF
KLLLTSNLML EGKYFRAFAA FAGCNVVLAT CAAALCALIA PAAAGSGIPE VKAYLNGIDA
HSILAPSTLL VKIFGSILGV AAGFVVGKEG PMVHTGACIA NLLGQGGSRK YHLTWNWLKY
FKNDRDRRDL ITCGAAAGVA AAFRAPVGGV LFALEEIASW WRSALLWRTF FTTAVVAMVL
RSLIQFCRSG KCGLFGQGGL IMFDVNSGVS NYNTIDVLAI ILIGVLGGLL GSLYNYLVDK
VLRTYSVINE RGPAFKILLV MTVSILTSCC SYGLPWLARC TPCPAGLEEK CPTIGRSGSY
KNFQCPPGHY NDLASLFLNT NDDAIRNLFS SNNSNEFHIS SLLVFFAGVY CLGIITYGIA
IPSGLFIPVI LAGASYGRIF GRALGSLSNL NVGLFSLLGA ASFLGGTMRM TVSICVILLE
LTNNLLMLPL VMLVLLISKT VADSFNKGVY DQIVKMKGLP FLEAHAEPFM RH
//
