ID A0A1S4CT74_TOBAC Unreviewed; 462 AA.
AC A0A1S4CT74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Clathrin interactor EPSIN 2-like {ECO:0000313|RefSeq:XP_016504311.1};
GN Name=LOC107822293 {ECO:0000313|RefSeq:XP_016504311.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016504311.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016504311.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
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DR RefSeq; XP_016504311.1; XM_016648825.1.
DR AlphaFoldDB; A0A1S4CT74; -.
DR SMR; A0A1S4CT74; -.
DR STRING; 4097.A0A1S4CT74; -.
DR PaxDb; 4097-A0A1S4CT74; -.
DR GeneID; 107822293; -.
DR KEGG; nta:107822293; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0030125; C:clathrin vesicle coat; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR CDD; cd03571; ENTH; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR12276:SF91; CLATHRIN INTERACTOR EPSIN 2-RELATED; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 18..150
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 149..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..299
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 50719 MW; 565288C2F0D4AF35 CRC64;
MKKAFGQTVR DIKRGVNKKV LKVPSIEQKV LDATSNEPWG PHGSLLADIA QASRNYHEYQ
MIMAVIWKRI SDTGKNWRHV YKALTILDYL VACGSERVID EIREHVYQIS TLSDFQYIDS
SGRDQGSNVR KKSQSLVVLV NDKERIQEVR QKAATNRDKF RNTSVGDMHQ PGSYSSSGGY
GDRYEEDRYG GRDEERNGYG RDEEKYGRYG DSYSRDGDRY GRGYDERSRD GNRDDDHRGR
SRSVDDYSYD SRSRSSDRDR NRAYDDDGQY SSRGSGARAE DRSQDGSVTD MRLERRFSEQ
NLDAPPSYEE AIGASRSPTH SERNGETPSA SAPKSSSPHS IGSPNQATTP APAPTAASLP
TPVPAAAPPE NKDIESFDEF DPRASFSVAG AQSNGAMPTT SGGTEVNLLG SLSEPFSSNS
LALVSATTTT SEVNPFGPTS SEPMFGGASP ASSVPNQVGF SS
//
