ID   A0A1S4CZR3_TOBAC        Unreviewed;       547 AA.
AC   A0A1S4CZR3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Transcription initiation factor TFIID subunit 6-like isoform X1 {ECO:0000313|RefSeq:XP_016506665.1};
GN   Name=LOC107824422 {ECO:0000313|RefSeq:XP_016506665.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016506665.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016506665.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF6 family.
CC       {ECO:0000256|ARBA:ARBA00007688}.
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DR   RefSeq; XP_016506665.1; XM_016651179.1.
DR   AlphaFoldDB; A0A1S4CZR3; -.
DR   STRING; 4097.A0A1S4CZR3; -.
DR   PaxDb; 4097-A0A1S4CZR3; -.
DR   GeneID; 107824422; -.
DR   KEGG; nta:107824422; -.
DR   OrthoDB; 1529at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR   GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR   CDD; cd08050; TAF6C; 1.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR037796; TAF6.
DR   InterPro; IPR011442; TAF6_C.
DR   InterPro; IPR046344; TAF6_C_sf.
DR   InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR   PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR   PANTHER; PTHR10221:SF17; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6-LIKE ISOFORM X1; 1.
DR   Pfam; PF02969; TAF; 1.
DR   Pfam; PF07571; TAF6_C; 1.
DR   SMART; SM00803; TAF; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          2..68
FT                   /note="TATA box binding protein associated factor (TAF)
FT                   histone-like fold"
FT                   /evidence="ECO:0000259|SMART:SM00803"
SQ   SEQUENCE   547 AA;  60742 MW;  056D47700D7DF857 CRC64;
     MSIVPKETIE VIAQSIGISN LSPDVLPALA ADVEYRIREI MQEAIKCMRH SKRTTLSTDD
     VDSALTLRNV EPIYGFASGD PLRFRRAAGH KDLFYIEEKD VEFKDVIEAP LPKAPLDTAL
     FAHWLAIEGV QPAIPENPPL EALAPPADNR KSEYKEDGVP VDLKIPVKHV LSRELQLYYD
     KITELTVNKS NSPLFKEALA SLATDPGLHP LVPYFTYFVA DEVARNLNNF DLLFALMRLV
     WSLLQNSHLH IEPYLHQSMP SVMTCLVAKR LGNKFSDNHW QLRDFTAKLV ALICRRYGHV
     YHSLQPRITK TLLHAYLDPT KALPQHYGAI QGLAALGSGV VRLLVLPNLE AYLRLLEPEM
     QLEKQKNEMK RHEAWRVYGA LMSAAGLCMY EHFKMLPASL SPSNWIFLKN KCKVATTLSN
     KRKASMDDMI SQPPPKKLMT DGPASPMLSS SLPVGIQGAI GGNATTLGVT DASLSSGPQG
     LQNENANNGM RSSRREIAGG KIQKAPAAFG QASKKDMDAA NLLPPLFEYF GDSMLFFAPS
     PELSFFL
//