ID   A0A1S4D0P2_TOBAC        Unreviewed;       685 AA.
AC   A0A1S4D0P2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
GN   Name=LOC107824673 {ECO:0000313|RefSeq:XP_016506956.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016506956.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016506956.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC       pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC   -!- SIMILARITY: Belongs to the CASP family.
CC       {ECO:0000256|ARBA:ARBA00006415}.
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DR   RefSeq; XP_016506956.1; XM_016651470.1.
DR   AlphaFoldDB; A0A1S4D0P2; -.
DR   STRING; 4097.A0A1S4D0P2; -.
DR   PaxDb; 4097-A0A1S4D0P2; -.
DR   GeneID; 107824673; -.
DR   KEGG; nta:107824673; -.
DR   OMA; KNARYSC; -.
DR   OrthoDB; 74668at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR012955; CASP_C.
DR   PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14043:SF2; HOMEOBOX PROTEIN CUT; 1.
DR   Pfam; PF08172; CASP_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        636..657
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          437..662
FT                   /note="CASP C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08172"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          476..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          126..221
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          254..363
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          433..460
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          507..548
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        476..497
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   685 AA;  79292 MW;  F68E205924C9CB9A CRC64;
     MDPQEGVSER DKAKPTSSST PLAAVSTYWR DFDLEKERSI LDEQGLRIAE NQDISQKNRR
     KLAESTRDFK KASKEEKLSL FNSLLKGYQE EVDNLTKRAK YGENAFLNIY QKLYEAPDPY
     PIIASIAEKD SKISELESEN RKMKVELEEF RMEATHLKNQ QATIRRLEER CRQLEQQMEE
     KVKEVVEIKQ RSLAEENQKT LEVLKEREQL LQDQLRQAQE SVSTMQKLHE LAQSQLFEVH
     AQSEGERAAK QSEVSLLMDE VERAQTRLLS LEREKGLLRS QLQTATEDND HKNSDNLDAN
     SALETSLIAK EKIISELNTE LHNLENALSN EREQHMNEIK RLNALLNEKE VALEELKKEL
     QTRPTTKVID DLRKKVKILQ AVGYNTIEAE DWEVATSGEE MSKLESLLLD KNRKMEHELT
     QLKFQLSERT SSLDSSEAKI VELTAKLNEQ QRLVQKLEDD ILKGYSSKDR KNTLIDDWDL
     SESGGKEASE NAEQRHVSSD QDQNSMLKVI CNQRDRFRTR LQETEEEIRR LNETIGVLTS
     ELEKTKADNV KLYGKIRYVQ DYNSERVISR GSKKYAEDLE SGFSSDVESK YKKMYEDDIN
     PFAAFSKKER DQRYKDLGLR DKITLSSGRF LLGNKYARTF AFFYTIGLHI LVFTCLYRMS
     ALSNLSHGSE ESFVGDKTIN LPHAL
//