ID A0A1S4D2Q9_TOBAC Unreviewed; 763 AA.
AC A0A1S4D2Q9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN Name=LOC107825226 {ECO:0000313|RefSeq:XP_016507554.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016507554.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016507554.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR RefSeq; XP_016507554.1; XM_016652068.1.
DR AlphaFoldDB; A0A1S4D2Q9; -.
DR GeneID; 107825226; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 141..408
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 545..697
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT REGION 251..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..481
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..571
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..731
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..763
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 763 AA; 85018 MW; 8F63A9CAAB6F0F40 CRC64;
MSPISGRHGP SEVTAEGIAA SGLTSEKLSL PNLQSKMKCD PEGYESELTL VYSQFKSSME
LFEQQAALNF TSLSGVSTDP TVSKDLGERA MFLSHVTPFY PKQLVNFPKE LAQLLRSSAR
TLPSGLRVHV TQALILLLNR KQEDEAKAKR ALITLCELHR RKVWFDDRTA NAVCSACFHS
SSRIMVASLS FILDYEKIED DSDSDMADSE DEQTATQPQV VVNKEAIYKA NNKGTSASKR
KKQAKLQRVV RSMKKQQRMQ SDNSGTGYSS PLNHLKDAQG FAEKLFSRLQ TCNERFEVKM
MMLKVIARTV GLHHLILLNF YPYLQRYVQP HQRDVTNLLA AAVQACHDMV PPDAVEPLFK
QIVNQFVHDR SRPEAISVGI NVIREICLRM PLLMTEDLLQ DLVLYKKSNE KAVSSSARSL
LTLFREVCPS LLVKKDRGRP TNPKARPKAF GEVSVANSIP GIELLEQEDN GSDDDIEEGS
VGLSDHDDQS DEDVDPGKED ASCEKDGDDA SDGESGDSSG DDCEIDDACD TDEDNIAQAA
EEFSENDDAI DSTDATEDDE SDGEEEDIDD SKMQDNNSWA SEEDDVDEKE SKGIKRRISD
IDVNAASNSL RALKKLAGAK MEHNSLNMED GILSNEDFQR IKELKAKKDA RTVLAQHGFK
IPSSDQLSTK RVDAAKLEAN IRKKLSKEER LAIIRAGRED RGRYQAKTAL KKKKTGGSSN
RQKESKKCMP SAAKKAKVAR SKLDKKRKQQ RAGKQFRGRK AWK
//
