ID A0A1S4D652_TOBAC Unreviewed; 762 AA.
AC A0A1S4D652;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Centromere/kinetochore protein zw10 homolog {ECO:0000313|RefSeq:XP_016508887.1};
GN Name=LOC107826424 {ECO:0000313|RefSeq:XP_016508887.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016508887.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016508887.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}.
CC -!- SIMILARITY: Belongs to the ZW10 family.
CC {ECO:0000256|ARBA:ARBA00006245}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016508887.1; XM_016653401.1.
DR AlphaFoldDB; A0A1S4D652; -.
DR STRING; 4097.A0A1S4D652; -.
DR PaxDb; 4097-A0A1S4D652; -.
DR GeneID; 107826424; -.
DR KEGG; nta:107826424; -.
DR OMA; THWVAQH; -.
DR OrthoDB; 1204040at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:1990423; C:RZZ complex; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IBA:GO_Central.
DR Gene3D; 1.10.357.150; -; 1.
DR InterPro; IPR046362; Zw10/DSL1_C_sf.
DR InterPro; IPR048343; ZW10_C.
DR InterPro; IPR048344; Zw10_middle.
DR InterPro; IPR009361; Zw10_N.
DR PANTHER; PTHR12205; CENTROMERE/KINETOCHORE PROTEIN ZW10; 1.
DR PANTHER; PTHR12205:SF0; CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG; 1.
DR Pfam; PF20666; ZW10_C; 1.
DR Pfam; PF20665; Zw10_middle; 1.
DR Pfam; PF06248; Zw10_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 38..129
FT /note="Centromere/kinetochore protein zw10 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06248"
FT DOMAIN 178..414
FT /note="Centromere/kinetochore protein zw10 middle"
FT /evidence="ECO:0000259|Pfam:PF20665"
FT DOMAIN 450..576
FT /note="Centromere/kinetochore protein zw10 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20666"
SQ SEQUENCE 762 AA; 86340 MW; 3CD9B3C0DC88D501 CRC64;
MDVLFNSINV RDLLSSPNID DVTSPLSAPD LRLLINRLQV RSVDIKSKVR QYILSHYSDF
STLFSQCSDV VSRSEHLSSE VSNLIQLISD HPVEVETKAV IDDIVIRNRE LKEKRELLGL
LAVVLELSDK LRFVKEEIKV GRVEQAAEAL RELKAVLVTS SNETTAFEER QPLVYGLLKD
EWTKCFEEMQ EVLLRCMDNA VWFEQENYTV HLKHQSNIKG IDGIELQTVL KAMDAVGIMD
YGLSKVADLM IKHVIAPVVS FRSTIVVEET NQESRNGAEA NLKILPSADP NVDSMDGGSM
YSVLVDIVKF ISKSLCFGNC TWMICFGRLT WPRMSDLIIS NFLSKNVPDD ASKLADFQKI
IKCTSDFEES LKELMFIASS DGKDERLSKF ADNVEVHFAS RKKVEILAKA RNLLLQSDFR
LPEDGTRRHS KVKDDKKSES SSDLVVNLLF TSERCVVSEA ASGLMKLVHG TLKDVCLSSP
RVGLEFYHAA RDSLLLYEAV IPVKFERQLD SINHSAVLIH NDCHYLSQEI LGLAFEYRSD
FPASIRELVF ADLAPRFQLL AEEVLRRQIK LVIYNLKQAI DGADGFQNTH QMKQYESAKL
SIDQVIFILE KVYIIWHHLL LPSAYKRSMS MVLEAVFSRI ANDILLLDDI AAEETLQLQR
LIHLLFENLS SLLDSVVAIN QSGKLQESPT QTLDDLIPSL RKLRKLADLL DIPLKSVTEA
WEAGELVNCG FTQTEVEDFI RAIFADSPLR KECLRRIESI CY
//
