ID A0A1S4DKJ3_TOBAC Unreviewed; 255 AA.
AC A0A1S4DKJ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cyclin-dependent kinase inhibitor 5-like {ECO:0000313|RefSeq:XP_016513903.1};
GN Name=LOC107830774 {ECO:0000313|RefSeq:XP_016513903.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016513903.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016513903.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the CDI family. ICK/KRP subfamily.
CC {ECO:0000256|ARBA:ARBA00010274}.
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DR RefSeq; XP_016513903.1; XM_016658417.1.
DR AlphaFoldDB; A0A1S4DKJ3; -.
DR STRING; 4097.A0A1S4DKJ3; -.
DR PaxDb; 4097-A0A1S4DKJ3; -.
DR GeneID; 107830774; -.
DR KEGG; nta:107830774; -.
DR OMA; IPTAHDM; -.
DR OrthoDB; 451632at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:InterPro.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR Gene3D; 4.10.365.10; p27; 1.
DR InterPro; IPR003175; CDI_dom.
DR InterPro; IPR044898; CDI_dom_sf.
DR InterPro; IPR044275; KRP.
DR PANTHER; PTHR46776; CYCLIN-DEPENDENT KINASE INHIBITOR 4-RELATED; 1.
DR PANTHER; PTHR46776:SF41; CYCLIN-DEPENDENT KINASE INHIBITOR 5-LIKE; 1.
DR Pfam; PF02234; CDI; 1.
DR PIRSF; PIRSF017811; CDK_inhib_pln; 1.
PE 3: Inferred from homology;
KW Protein kinase inhibitor {ECO:0000256|ARBA:ARBA00023013};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 209..253
FT /note="Cyclin-dependent kinase inhibitor"
FT /evidence="ECO:0000259|Pfam:PF02234"
FT REGION 38..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 255 AA; 28542 MW; 5321CDB39C247E01 CRC64;
MGKYMRKSKT TGEVALLEVS HTQSSPLGVR TRAKTLALQR LQKSNSNGNG SGGDGGGGGG
GSYLQLRSRR LEKPNHEGKR QKYPLKDPNL PNPVKNNQSS RTSSTRLRKG HSWNSGSVEE
RLGEEKKEEI NLQEIQNEIK HNSCGEGGVE ASFGENLLEF EGRERTTRES TPCSLIRDAD
NIQTPGSSTR PTNATEDNSR VPNSTRRLIP TAREMNDFFG GPEEQQQRQF IEKYNFDPVN
DKPLPGRYEW EKVDR
//
