ID A0A1S4DKZ5_TOBAC Unreviewed; 1195 AA.
AC A0A1S4DKZ5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Myosin-2-like isoform X1 {ECO:0000313|RefSeq:XP_016514069.1, ECO:0000313|RefSeq:XP_016514070.1};
GN Name=LOC107830904 {ECO:0000313|RefSeq:XP_016514069.1,
GN ECO:0000313|RefSeq:XP_016514070.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016514070.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016514069.1, ECO:0000313|RefSeq:XP_016514070.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR RefSeq; XP_016514069.1; XM_016658583.1.
DR RefSeq; XP_016514070.1; XM_016658584.1.
DR STRING; 4097.A0A1S4DKZ5; -.
DR PaxDb; 4097-A0A1S4DKZ5; -.
DR GeneID; 107830904; -.
DR KEGG; nta:107830904; -.
DR OrthoDB; 5489458at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0030050; P:vesicle transport along actin filament; IBA:GO_Central.
DR CDD; cd01383; MYSc_Myo8; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036022; MYSc_Myo8.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF769; MYOSIN-2-LIKE ISOFORM X1; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 150..199
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 203..862
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..764
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1048..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 941..1029
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 15..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1081
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 294..301
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1195 AA; 136009 MW; 640CFE97B9C1EAB4 CRC64;
MLSVSAPSRT RSSLEEMLES LKQRDENEKP KDIPPALPAR PKLASRTRPP SPKRTLPNNT
KENRSVVELE NGRKEEVKGK RGNMFGAKKG KEMIMEFSES PYVNSFSVEK EYRQRFWEKD
GAKLDNNRLP YSLPKFREDE WNDNISYFIE KKLRVWCRLK SSQWEPGHIQ STSGDKASVL
LSDGSVVAVP VGELLPANPD ILSGMDNLIQ LCYLNEPSVL HNLQYRYAQD RIYTKTGPVL
IAVNPFKEIQ LYGNELVTAY RQKLLDDPHI YSTADTAYSQ MMEDEINQSI IISGESGSGK
TETAKYAIEY LAMISGGNNR IESGVLQTSC ILEAFGNAKT PRNNNSTRFG KLIEIYFSAE
GGICGANVQT SLLEKSRVVQ LAHGERSYHI FYQLCAGAPS ALRDKLKLKG ASDYNFLNQS
DCLVIHDVHD AKKFHMLVKA LNTMGMSESD QEHAFQMVAA VLWLGNITFQ AISSENYVEV
AQSEAVINAA SLLGCSANDF MLALSTRRMQ TGKDKVVKSL TMQQAIDTRD ALAKFIYANL
FDWIVDKINK SLAMGKEKTA RTINIVDIYG FESFEKNSFE QLCINYANER LQQHFNRHLF
KLEQEEYELD GIDWTKVDFQ DNQECLDLFE KKSIGLISLL DEESNFHKAT DLTFANKLKQ
HLKANPCYIG DREEFGIHHY AGEVIYDTSG FLEKNRDTVH SDVIQLLSSS SEHLPKSFAS
SFANQSADFQ KQTVATKFKD LLFKLMQQLE STAPHFVCCI KPNNKQVPGM YNNDLVFEQL
RCSGLLDIAR ISRSGYPTRM THQEFSKRYG VLLPQVHESK DPLSMSVAIL RQFDILPEMY
QVGYTKLYFR AGQIAALEDV RKQVLQGTLE VPKCYSGHCA RRHFHELEGV IIILQSFVRG
EIARRQYNAS LESKRKAANK ENDKQLVAVV QIQSAIRCWL AQRHLNQLQS LKKLNQDREK
QGRKTSEVKQ DFPAEILPSV VEDFERRVMV AEASLDEKDK ENAALKEQVN QLEARWSDYE
VRMRSMEEMW QKQMVSLQAS LAAAKKSLGV DNPAGHPGKR EGSQSPCGYD SEDTTTMGTH
TPGGSTPIEF ASNGVDFGGI RENNGGLCVV NYLNREFELR RQNFDDEAMA IAQLKSEQLH
STNPAEDFRR LRHRFEEWKK DYKARLKETK AKVHKLSYSE AEKTRRNWWG KKSKR
//
