ID A0A1S4DM15_TOBAC Unreviewed; 409 AA.
AC A0A1S4DM15;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=mannan endo-1,4-beta-mannosidase {ECO:0000256|ARBA:ARBA00012706};
DE EC=3.2.1.78 {ECO:0000256|ARBA:ARBA00012706};
GN Name=LOC107831024 {ECO:0000313|RefSeq:XP_016514219.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016514219.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016514219.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random hydrolysis of (1->4)-beta-D-mannosidic linkages in
CC mannans, galactomannans and glucomannans.; EC=3.2.1.78;
CC Evidence={ECO:0000256|ARBA:ARBA00001678};
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
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DR RefSeq; XP_016514219.1; XM_016658733.1.
DR AlphaFoldDB; A0A1S4DM15; -.
DR SMR; A0A1S4DM15; -.
DR STRING; 4097.A0A1S4DM15; -.
DR PaxDb; 4097-A0A1S4DM15; -.
DR GeneID; 107831024; -.
DR KEGG; nta:107831024; -.
DR OMA; WIQEMAT; -.
DR OrthoDB; 2717493at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016985; F:mannan endo-1,4-beta-mannosidase activity; IBA:GO_Central.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045053; MAN-like.
DR PANTHER; PTHR31451:SF59; MANNAN ENDO-1,4-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR31451; MANNAN ENDO-1,4-BETA-MANNOSIDASE 7; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|RuleBase:RU361153};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..409
FT /note="mannan endo-1,4-beta-mannosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010197436"
FT DOMAIN 75..346
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
SQ SEQUENCE 409 AA; 46220 MW; 2B904A471F490991 CRC64;
MAYFTRMTSS FFALLFFLVL ACEARVPGKT SGGFVRTNGA HFVLNRSPFL FNGFNSYWLM
HVASDPSERY KVSEVFQEAS AARLSVCRTW AFSDGGDTAL QISPGVYDER VFQGLDFVIT
EARKYGIRLI LSFVNNYNDF GGRAQYAQWA RNAGVRINSE DDFYTHPVLK DYYKNHVRKV
VTRLNTITGM AYRDDSTIMA WELMNEPRCK ADYSGKIVNA WIQEMATFVK SIDRKHLLEI
GMEGFYGDSM PEKKQFNPGY QVGTDFISSH LIKEIDFATI HAYTDQWLSG QNDNAQMAFM
QRWITSHWQD SSTILKKPLV LAEFGKSSKD PGFNLNARDT YMSSVYRNIY NYAKSGGTMG
GSLVWQLVAQ GMENIDDGYS IILAQNPSTA GIISGQSHAM TTLAHLVNN
//
