ID A0A1S4DS67_CUCME Unreviewed; 679 AA.
AC A0A1S4DS67;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cysteine-rich receptor-like protein kinase 26 isoform X1 {ECO:0000313|RefSeq:XP_016898831.1};
GN Name=LOC103489186 {ECO:0000313|RefSeq:XP_016898831.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_016898831.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|RefSeq:XP_016898831.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016898831.1; XM_017043342.1.
DR AlphaFoldDB; A0A1S4DS67; -.
DR GeneID; 103489186; -.
DR InParanoid; A0A1S4DS67; -.
DR OrthoDB; 1053684at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.430.20; Gnk2 domain, C-X8-C-X2-C motif; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR27002:SF844; CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 27-RELATED; 1.
DR PANTHER; PTHR27002; RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE SD1-8; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF01657; Stress-antifung; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51473; GNK2; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|RefSeq:XP_016898831.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Receptor {ECO:0000313|RefSeq:XP_016898831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_016898831.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..679
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010295758"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..138
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 144..251
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 381..673
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 409
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 679 AA; 76334 MW; 5961FAC223FC3EFB CRC64;
MAASTFVFSI TTLSLLVLAL INHPPLAFAQ PRFSRYVCVE YTINNHTTDG AAYKANLNHL
LTTLTTDHHI DYGFYNSSYG AGENRANVIG LCRGNISPET CRKCLNDSRD LLPVRCPTHK
EAIGWYQDCM LRYSDRPILG SMELSPSIPM GYPFNASDPE RFTQAARKLI ESLIAKASAG
DSHVKFSTGN TTLADFPTIY AFAQCTPDLS RRQCNECLTE ALAIIQDCCV GNLFGRVATP
SCLFRYGDDS LIQWPTSPWL SSSPSPVSSL LNRTTHHGNK SSLSRTFIPV IVPMAVVVLL
LTITIYMGQR KYSPTTRGEE CMLIKLVFLF FKLNQPLEMD LKFPSTIIPC FEATGQTEEE
MARMGFMQYD FDTIRIGTDK FSDENKVGEG GFGAVYKGKL PNGRIVAVKR LSQASRQGDV
EFKNEVVLLS KLRHRNLVKL LGFSFKENEE LLIYEFLQNA SLQKFIFDPL KPGGLDWTTR
YKIIEGITRG LVYLHEDSRI KIVHQNLKAH NILLDAEMNA KISDSGIARL FALEQTQDDT
CTIIDNVGCM APEYIRYGHL SSKSNVFSYG VLVLEIVTGH KENYQTVSNI ENTKYPLISY
ARRNWREGRT LLNIVDPTIE IQSETTMNEV TKCIHIGLLC TQEDVDERPK MTDVLLMLKS
DLADFPKPSQ PSFFMNTIS
//
