ID   A0A1S4DTX6_CUCME        Unreviewed;       327 AA.
AC   A0A1S4DTX6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Twinkle homolog protein, chloroplastic/mitochondrial isoform X5 {ECO:0000313|RefSeq:XP_016899155.1};
GN   Name=LOC103488713 {ECO:0000313|RefSeq:XP_016899155.1};
OS   Cucumis melo (Muskmelon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX   NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_016899155.1};
RN   [1] {ECO:0000313|Proteomes:UP000089565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX   PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA   Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA   Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA   Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA   Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA   Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA   Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA   Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT   "The genome of melon (Cucumis melo L.).";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN   [2] {ECO:0000313|RefSeq:XP_016899155.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016899155.1; XM_017043666.1.
DR   AlphaFoldDB; A0A1S4DTX6; -.
DR   GeneID; 103488713; -.
DR   OrthoDB; 469355at2759; -.
DR   Proteomes; UP000089565; Unplaced.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   CDD; cd01029; TOPRIM_primases; 1.
DR   Gene3D; 3.40.1360.10; -; 1.
DR   InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR027032; Twinkle-like.
DR   PANTHER; PTHR12873; T7-LIKE MITOCHONDRIAL DNA HELICASE; 1.
DR   PANTHER; PTHR12873:SF6; TOPRIM DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13662; Toprim_4; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF56731; DNA primase core; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000089565}.
FT   DOMAIN          181..270
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|SMART:SM00493"
SQ   SEQUENCE   327 AA;  37431 MW;  607A2081D257CA16 CRC64;
     MLHRCRRQVL REKMDLIGIV CDEHCIPGKY YCLFCPKCKG GRLMERSLSL HVIPTGDFAM
     WRCFRFECGW AGRIFADGRL AFNGFSKTEK MVGRSSKESL VLEPLCDELI SYFSMRMISQ
     ETLERNVVMQ VVGRQQVAIA FTYRQNGQLV GCKYRTMDKR FWQEKGTAKF LYGIDDINDA
     DELIIVEGEM DKLSVEEAGF LNCISVPGGA PSKVSTDTIP PIEKDSAYQY LWGCKDYLDK
     VSRIILATDS DVPGQALAEE LARRLGKHRC WRVDWPYKDG FNRFKDANEV LVHLGPDALK
     NAIQDAKFYQ LSISISIQKE EGLFQEH
//