ID   A0A1S4DWK7_CUCME        Unreviewed;       418 AA.
AC   A0A1S4DWK7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Biotin--protein ligase 2-like isoform X1 {ECO:0000313|RefSeq:XP_016900372.1};
GN   Name=LOC103489963 {ECO:0000313|RefSeq:XP_016900372.1};
OS   Cucumis melo (Muskmelon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX   NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_016900372.1};
RN   [1] {ECO:0000313|Proteomes:UP000089565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX   PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA   Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA   Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA   Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA   Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA   Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA   Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA   Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT   "The genome of melon (Cucumis melo L.).";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN   [2] {ECO:0000313|RefSeq:XP_016900372.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the biotin--protein ligase family.
CC       {ECO:0000256|ARBA:ARBA00009934}.
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DR   RefSeq; XP_016900372.1; XM_017044883.1.
DR   AlphaFoldDB; A0A1S4DWK7; -.
DR   InParanoid; A0A1S4DWK7; -.
DR   OrthoDB; 317678at2759; -.
DR   Proteomes; UP000089565; Unplaced.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   CDD; cd16442; BPL; 1.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   NCBIfam; TIGR00121; birA_ligase; 1.
DR   PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR   PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR   Pfam; PF03099; BPL_LplA_LipB; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|RefSeq:XP_016900372.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000089565}.
FT   DOMAIN          119..309
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
SQ   SEQUENCE   418 AA;  47286 MW;  7444E6D64486CF69 CRC64;
     MLLANQLRYF GRRDSRFVFS VLNSSSFWSL SRIVASPPTP AISINERERR RLFSLSSASG
     MDASPTCSLV LSGKTAAENE TAKLLKRNDT LKLPDDTEIS VLLHSEKDKP LEENGFRIDL
     YLNALSTDTF GRFLIWSPRV PSTQDVISHN FSNLPLGAVC VADVQFKGRG RSKNLWESPP
     GCLMFSFTIQ MEDGRTVPLL QYVISLAITE AIKDICDKEG LPYIDLKIKW PNDLYVNDLK
     VGGVLCTSTY RLKKFNVTAG IGLNVENDKP STCLNEALTD LSSTPYKFRK EDILAFFFNK
     FERLYDVFIN QGFRALEELY YQTWLHSGQR VVVQEKKEDQ VVENVVTIQT FACFFIQGLT
     SSGYLLAIGD DNQMCELHPD GNSQSMLHAL LFLHCSVHNP KHEFISKCSG YRYMILEG
//