ID A0A1S4DXR1_CUCME Unreviewed; 635 AA.
AC A0A1S4DXR1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Probable acyl-activating enzyme 18, peroxisomal isoform X1 {ECO:0000313|RefSeq:XP_016900763.1};
GN Name=LOC107991018 {ECO:0000313|RefSeq:XP_016900763.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_016900763.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|RefSeq:XP_016900763.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016900763.1; XM_017045274.1.
DR AlphaFoldDB; A0A1S4DXR1; -.
DR InParanoid; A0A1S4DXR1; -.
DR OrthoDB; 760232at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR44378; ACYL-ACTIVATING ENZYME 17, PEROXISOMAL-RELATED; 1.
DR PANTHER; PTHR44378:SF1; ACYL-ACTIVATING ENZYME 18, PEROXISOMAL-RELATED; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000089565}.
FT DOMAIN 126..177
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 204..554
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 635 AA; 70516 MW; 188660EECE28D3E4 CRC64;
MGKSIWELGI EDLVRTGLNL HEAVEFNRIL KNVLSTTQRS KPTEVWRELM ARRALKPTHP
FELHRLLYYS VYANWNISTS GPPPYWFPSL DQSKLTNLGK IMELQGPKLL GASYKDPISS
FSLFQKFSIQ NPEIYWSIVL QELSVTFQKA PRCILDRTEK PNGRWLPDSM LNIAECCLRS
SSRLLRDDNS LAIVWRDEGC DNSNVNHMTL KQLREKVTLV ANALDATFSK GDAVAIDMPL
TVDAVVIYLA IVLAGLVVVS IADSFAANEV AVRLLISKAK GIFTQDFILR GGKKYPLYSR
VIEGGSCKAI VIPVTGNRLE VDLREQDLSW EEFLSTAKEF PRSNCYSPMY HSIDAVTNIL
FSSGTTGKPK AIPWTQLSPI RCAADSWAHM DVQAGDVFCW PTNLGWAMGP VSVYSSLLVG
ATLALYHGSP LGHGFGKFVQ DAGVTILGTI PSLVKTWKDT RCMEGLNWTK IRYFASTGET
SNVDDDLWLS SRSYYKPLFE CCGGTELGSS FIVGSPVQPQ AFGAFSTASM TTGFVILDEH
GIPFPEDQPC IGEIGLFPIY LGASNELLNA DHDEVYFKGM PIYNGMQLRR HGDIIRRTVG
GYLIVQGRAD DTMNLGGIKV RIKQAIDHKI VNNKA
//
