ID A0A1S4E1L7_CUCME Unreviewed; 1065 AA.
AC A0A1S4E1L7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Calcium-transporting ATPase 4, endoplasmic reticulum-type-like {ECO:0000313|RefSeq:XP_008457516.1, ECO:0000313|RefSeq:XP_016902118.1};
GN Name=LOC103497190 {ECO:0000313|RefSeq:XP_008457516.1,
GN ECO:0000313|RefSeq:XP_016902118.1};
GN Synonyms=103497190 {ECO:0000313|EnsemblPlants:MELO3C020683.2.1};
OS Cucumis melo (Muskmelon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis.
OX NCBI_TaxID=3656 {ECO:0000313|Proteomes:UP000089565, ECO:0000313|RefSeq:XP_016902118.1};
RN [1] {ECO:0000313|Proteomes:UP000089565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DHL92 {ECO:0000313|Proteomes:UP000089565};
RX PubMed=22753475; DOI=10.1073/pnas.1205415109;
RA Garcia-Mas J., Benjak A., Sanseverino W., Bourgeois M., Mir G.,
RA Gonzalez V.M., Henaff E., Camara F., Cozzuto L., Lowy E., Alioto T.,
RA Capella-Gutierrez S., Blanca J., Canizares J., Ziarsolo P.,
RA Gonzalez-Ibeas D., Rodriguez-Moreno L., Droege M., Du L.,
RA Alvarez-Tejado M., Lorente-Galdos B., Mele M., Yang L., Weng Y.,
RA Navarro A., Marques-Bonet T., Aranda M.A., Nuez F., Pico B., Gabaldon T.,
RA Roma G., Guigo R., Casacuberta J.M., Arus P., Puigdomenech P.;
RT "The genome of melon (Cucumis melo L.).";
RL Proc. Natl. Acad. Sci. U.S.A. 109:11872-11877(2012).
RN [2] {ECO:0000313|EnsemblPlants:MELO3C020683.2.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2023) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_008457516.1, ECO:0000313|RefSeq:XP_016902118.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_008457516.1; XM_008459294.2.
DR RefSeq; XP_016902118.1; XM_017046629.1.
DR EnsemblPlants; MELO3C020683.2.1; MELO3C020683.2.1; MELO3C020683.2.
DR GeneID; 103497190; -.
DR Gramene; MELO3C020683.2.1; MELO3C020683.2.1; MELO3C020683.2.
DR KEGG; cmo:103497190; -.
DR eggNOG; KOG0202; Eukaryota.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000089565; Unplaced.
DR Proteomes; UP000596662; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF4; CALCIUM-TRANSPORTING ATPASE 1, ENDOPLASMIC RETICULUM-TYPE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000089565};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 867..889
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 989..1009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1024..1045
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..99
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1065 AA; 116636 MW; 9F3B75FE0B6DD11B CRC64;
MGRGGENYGK KEIFAANSSK KETYPAWARD VQECLEIYQV NPDLGLSTEE VENKRKIYGY
NELEKHEGTS IFKLILEQFN DTLVRILLAA AVVSFVLAWY DGEEGGEMEI TAFVEPLVIF
LILIVNAIVG IWQENNAEKA LEALKEIQSE QASVLRNGKR TSIVAKELVP GDIVELRVGD
KVPADMRVLR LISSTFRVEQ GSLTGESEAV SKTSKTVPED TDIQGKKCMV FAGTTVVNGN
CICIVTQTGM STELGQVHCQ IQEAAQSEDD TPLKKKLNEF GELLTAIIGV ICALVWLINV
KYFLTWEYVD GWPANFKFSF EKCTYYFEIA VALAVAAIPE GLPAVITTCL ALGTRKMAQK
NALVRKLPSV ETLGCTTVIC SDKTGTLTTN QMAVAKIVAL GSRVGTLRAF DVEGTTYDPL
DGKIIGWLEG QLDANLQMLA KIAAVCNDAG VEKSGHHFVA SGMPTEAALK VLVEKMGLPE
GYDSSSVETN GDVLRCCQAW NKNEQRIATL EFDRDRKSMG VITNSKSGKK SLLVKGAVEN
LLDRSSFIQL LDGTIVNLDS DSKKYLLDCL REMSSSALRC LGFAYKEYLP EFSDYTVGDE
DHPAHQLLLD PSKYSTIESN LIFAGFVGLR DPPRKEVHQA IEDCKAAGIR VMVITGDNQN
TAEAICREIG VFGQHEAINS RSLTGKQFMT MSREDQKFHL RQDGGLLFSR AEPRHKQEIV
RLLKEDGEVV AMTGDGVNDA PALKLADIGI AMGIAGTEVA KEASDMVLAD DNFSTIVAAV
GEGRSIYDNM KAFIRYMISS NIGEVASIFL TAALGIPEGM IPVQLLWVNL VTDGPPATAL
GFNPPDNDIM KKPPRKSDDS LITTWILIRY LVIGLYVGLA TVGVFIIWYT HGSFLGIDLS
GDGHSLVSYS QLANWGQCPS WEGFSVSPFT AGDEVFNFDS DPCEYFRSGK IKASTLSLSV
LVAIEMFNSL NALSEDGSLL TMPPWVNPWL LLAMSVSFGL HFLILYVPFL AKIFGIVPLS
LNEWLLVLAV ALPVIIIDEI LKFIGRLTSG LRTSRPSRSS KQKSE
//
