ID A0A1S5VYU2_9VIRU Unreviewed; 1618 AA.
AC A0A1S5VYU2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Non-structural polyprotein {ECO:0000313|EMBL:AQP31145.1};
OS Bat badicivirus 1.
OC Viruses.
OX NCBI_TaxID=1958785 {ECO:0000313|EMBL:AQP31145.1};
RN [1] {ECO:0000313|EMBL:AQP31145.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27666390; DOI=10.1038/srep34209;
RA Yinda C.K., Zeller M., Conceicao-Neto N., Maes P., Deboutte W., Beller L.,
RA Heylen E., Ghogomu S.M., Van Ranst M., Matthijnssens J.;
RT "Novel highly divergent reassortant bat rotaviruses in Cameroon, without
RT evidence of zoonosis.";
RL Sci. Rep. 6:34209-34209(2016).
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DR EMBL; KX644945; AQP31145.1; -; Genomic_RNA.
DR Proteomes; UP000204462; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR CDD; cd23169; ps-ssRNAv-Picornavirales; 1.
DR Gene3D; 1.20.960.20; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR InterPro; IPR014759; Helicase_SF3_ssRNA_vir.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR Pfam; PF00910; RNA_helicase; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
DR PROSITE; PS51218; SF3_HELICASE_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000204462};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT TRANSMEM 189..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 351..528
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51218"
FT DOMAIN 1326..1459
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1618 AA; 181860 MW; CEBE1DD056957AC0 CRC64;
MTVQSKEKNT SVQNEKPHII SSHQCRKASY SSAYQATNAE QSFSPMWWAL HGVRGVSGLV
SETCATLLNY TYGEDHPESK KLEMAVSRIS LMSIQLAQNV SFSSIVVFLL QLTTEFGFTP
FDMIRKLIGL YSDARLCSTQ LIQSMGDAVK ALLVKMKVLG GDDEVVPDPI QQIGVNAEQS
MDLVDPSHAA AVAGILGGVA VILGAMFAGV QDYSANKGFL KSIAEFGSKT SKMKNGLYAL
LACVRDFSSF VKECVLNYFG TSPADSVVKA VDSLKFTFND EPVNAAQLFK VFAELNTPEG
EEVMSCDLEK LNKGTAICGV LSRVLSGQIA SAFNIPTGTV SLLSQSLRTF EGRVRNAGNK
QNVGNIRFVP YVIWLGGVPG GGKSVTMTHL SPDLMSALQH EDAERYQIPS QDNWTFTANF
TQEYHTGYNG QYQMRIDDVC QDKAGTLKQS SAMQFIQWVS SVPANMTQAA LEDKKCPFRS
KMVLCTSNEL WPNRTHEIMS NEAFLRRRNV LIKAVPSAKI DPGLNWGLEF YKMNPLNSSD
PGVKFESYYH MVKFILEDYK RHFAAQTTLI DKVNNGNSEG FLAFLAEQSC QRVEEPEEPP
ARPLTPDVFD DMPTRQWGVP GFEFDHPFVR GENWVAQNWA LEMDQTAFNR MMTVLFYCRF
PIYHFSATGR LTTPDLADHV VYEYDKVMIA SMRNYEWDTE YVQEAIAVAR RIYGRVNAEQ
SAGFEDGIFS VKDTISNLID AIVESTKRID VFWEKISSGW CWKILAGVSA MALVYFSVKR
FGPSGGSWRE MNADASYSHD VGRTKPRATM HTPSYNHEVG RSRPRAVQAV RSNFLDSIFH
KNVVKISWEG GPLDTFALNG IFIKDKVLLT CRHFFVGMDT DATLVVTRYP KYSSPVSCKV
AFKPENLVRV PGAEDAVLYN VESGVDNFRD ISKKFFSGSL PEVMTAATAS HYPSTETFIG
QVTAFTENEP VLYKMGTGAE MAEVIKGFIF QGLCLKGQSG SPLIADERVS RAPTLFGIQV
AISTQHDSSY FEALCQAQID DALSKFECEQ SMILQQEPHR YEQEDEEAWF DAPEYVQEMC
NSSLELVGRA KKVVPQPGKT RLLRSPLNEL FEKLPGEKQY LPSALRDRDV DILAKSMSGF
SREYGKICPR TLKRTLEQFI DEDQVIRAGG QRRLLDDDEL LNGIHGQGLK GVELKTSPGI
PLVFERAGHP GKTKWITMGD DNQRTMSPDA WDEFRKQEDM LRSGRRVPVT AYACLKDELR
TEEKVAAKKT RTFIILPMMF NLLIRKYFGT WISKQHSLAG RISSCVGIDV NRDWTDLSRK
LKAKGKDIED FDYSDWDRSL HPEWFSVYAD RVSAWYGDKP GSAGFVVRRA LMDQLVYMNV
QVGPWLMRTH GGNKSGCAIT AEINTDLHDM LVYYVWSRIC DERGTPTIQS LPHFRERVSL
ALYGDDMLKA TRADVTAWFN GDAMKKVISE LGMHITPGDK DESAGFRIKT LEEVTFLKRR
FISFDEDCGK VRAPLDKSVI QRIVLWIHAS DSAVDATSEN VRGALREAFF WGEDFFRDFR
SRCLQSWHRS RCSVRPFPTV GYQDVFDAWR AGHGDLLPAR YQFSEVPLVE QRGGTVDV
//
