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Database: UniProt
Entry: A0A1S6HIB8_9GAMM
LinkDB: A0A1S6HIB8_9GAMM
Original site: A0A1S6HIB8_9GAMM 
ID   A0A1S6HIB8_9GAMM        Unreviewed;       462 AA.
AC   A0A1S6HIB8;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   13-FEB-2019, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Sps_00034 {ECO:0000313|EMBL:AQS35259.1};
OS   Shewanella psychrophila.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=225848 {ECO:0000313|EMBL:AQS35259.1, ECO:0000313|Proteomes:UP000189545};
RN   [1] {ECO:0000313|EMBL:AQS35259.1, ECO:0000313|Proteomes:UP000189545}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WP2 {ECO:0000313|EMBL:AQS35259.1,
RC   ECO:0000313|Proteomes:UP000189545};
RA   Xu G., Jian H.;
RT   "Complete genome sequence of Shewanella psychrophila WP2, a deep sea
RT   bacterium isolated from west Pacific sediment.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP014782; AQS35259.1; -; Genomic_DNA.
DR   KEGG; spsw:Sps_00034; -.
DR   KO; K02313; -.
DR   BioCyc; GCF_002005305:SPS_RS00190-MONOMER; -.
DR   Proteomes; UP000189545; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000189545};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      159    372       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      370    439       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     167    174       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      321    341       {ECO:0000256|SAM:Coils}.
FT   COILED      439    459       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   462 AA;  52310 MW;  E78006F4B877883A CRC64;
     MAVSLWQQCL GRLQDELSSQ QFSMWIRPLQ AEMDGNTLVL YAPNRFVLDW VRDKYINIIN
     QFFTEQLGSD APKLRFDIGS KPAAPRPVQA TPAMAPPRVE MNSRPARTSF NVNTPEPAIM
     ANHRSNINPA YQFENFVEGK SNQLGKAAAL QVAENPGGAY NPLFLYGGTG LGKTHLLHAV
     GNSIIKNNPN AKVVYMHSER FVQDMVKALQ NNAIEEFKRY YRSVDALFID DIQFFANKDR
     SQEEFFHTFN ALLEGNHQVI LTSDKYPKEI DGVEDRLKSR FGWGLTVAIE PPELETRVAI
     LMRKAQESGI NLPDEVAFFI AKRLRSNVRE LEGALNRVIA NANFTGRPIT IDFVREALRD
     LLALQEKLVT IDNIQKTVAE YYKIKMADML SKRRSRSVAR PRQVAMALSK ELTNQSLPEI
     GDAFGGRDHT TVLHACRKIA QLREESHDIK EDYANLIRTL SS
//
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