ID A0A1S6IPU1_9LACT Unreviewed; 588 AA.
AC A0A1S6IPU1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=recQ_2 {ECO:0000313|EMBL:AQS53573.1};
GN ORFNames=BW727_101206 {ECO:0000313|EMBL:AQS53573.1};
OS Jeotgalibaca dankookensis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Jeotgalibaca.
OX NCBI_TaxID=708126 {ECO:0000313|EMBL:AQS53573.1, ECO:0000313|Proteomes:UP000188993};
RN [1] {ECO:0000313|EMBL:AQS53573.1, ECO:0000313|Proteomes:UP000188993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EX-07 {ECO:0000313|EMBL:AQS53573.1,
RC ECO:0000313|Proteomes:UP000188993};
RX PubMed=24554638; DOI=10.1099/ijs.0.057059-0;
RA Lee D.G., Trujillo M.E., Kang H., Ahn T.Y.;
RT "Jeotgalibaca dankookensis gen. nov., sp. nov., a member of the family
RT Carnobacteriaceae, isolated from seujeot (Korean traditional food).";
RL Int. J. Syst. Evol. Microbiol. 64:1729-1735(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; CP019728; AQS53573.1; -; Genomic_DNA.
DR RefSeq; WP_062472234.1; NZ_CP019728.1.
DR AlphaFoldDB; A0A1S6IPU1; -.
DR STRING; 708126.BW727_101206; -.
DR KEGG; jda:BW727_101206; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000188993; Chromosome.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AQS53573.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AQS53573.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000188993}.
FT DOMAIN 25..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 215..386
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 513..588
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 588 AA; 66674 MW; C3F56C3B7CAF38B2 CRC64;
MKKIETVLKE YYGYDHFRPG QEELIEAILK GQDALGIMPT GGGKSLCYQI PAICMEGTGI
VISPLISLMK DQVDALQTMG VRAGFINSQL DKATYLNTMD KALFGYYDLL YIAPERIASE
HFLNTISHMN INMVAVDEAH CISQWGQDFR PSYQTIPQLR DIVPEHVPFA AFTATATTQV
QEDISQQLRL QKPNKFVASF DRPNLYFSVV QSKKKSQDLL SRINEEGSTI IYCNTRKNVE
SVYHNLVKKG FDVTYYHAGI SAEERIKNQD DFIYDRKPIM VATNAFGMGI DKSNVRKVIH
YNMPLNMESY YQEAGRAGRD GAPSEAILFY SGQDIITNTF LIEQGNQPHA KEKLNRMITY
CKTGQCLRAY ILNYFDEHPE WERCEQCSNC DGHTETIDVT VDCQKILSCI HRMDQRFGAG
MVTDVLRGKN NQRIRSLQFD QLSTYGIMAK KTDERIKDII SLMIGDGYLA LSGDKYPILT
FTNKTNALLQ AQDKLLMTYK IVDKVAHDKV DTQEYDKELF EALKKLRFQI SKEIGKPPFV
VFTDKSLISM ASQLPTNDSA FLAIHGVGQS KLATYGAEFM AVIEAHKK
//
