ID A0A1S6L1F3_9CAUD Unreviewed; 808 AA.
AC A0A1S6L1F3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AQT27793.1};
OS Ralstonia phage RS-PI-1.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Autographiviridae; Okabevirinae; Ampunavirus; Ampunavirus RSPI1.
OX NCBI_TaxID=1958965 {ECO:0000313|EMBL:AQT27793.1, ECO:0000313|Proteomes:UP000224348};
RN [1] {ECO:0000313|EMBL:AQT27793.1, ECO:0000313|Proteomes:UP000224348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Su J., Sun H., Liu J., Guo Z., Fan G., Gu G., Wang G.;
RT "Isolation and complete genomic analysis of a novel lytic bacteriophage
RT infecting the Ralstonia solanacearum.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KY464836; AQT27793.1; -; Genomic_DNA.
DR Proteomes; UP000224348; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR019760; DNA-dir_DNA_pol_A_CS.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00447; DNA_POLYMERASE_A; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000224348}.
FT DOMAIN 477..726
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 808 AA; 90675 MW; 9E9797BAA181616A CRC64;
MNYTVWDIET STKTEFKRKA NPFSPENYVV CHGFSRGAIG AKDMGTPKGE YFGIGDALED
RIAACKNLPP DWFQKLLKGT KVLVGQNIKF DILYAIANPN SNCEANLAAW MEWVTSGGIL
WDIQLAEYLL RGMEQSSQMM SLDEIAPAYG GNVKFDEVKA LWNAGVPTIE IPEDLLMRYL
VGGDGEHGDI GNTELVFLKQ FEKAKKDGQL RSILLNMGSL IFTIEAERNG MFVDKELGLK
LAAELKEKLD LAVEQLRAYL PEDLPFDFNW SSRFHKSALI FGGPVKYKAR AVVKGDDGEP
VYYQKDEVHV LLADDTTLEL DAYMKLALEG TAPEAQRFAG GKNKGEVKTK KVKVKDIERG
PKTRIEDFEY HFDGFTKPDK RWASSEPGVY STAANVIEEL GNRDIPFLKT LSEVQAMTKD
LGTYFIVVDE ETGEEKGMLT LVQLDSIIHH SLNHTSTVTA RLSSSNPNLQ NLSKGQKSNV
KLVFRSRFGE EGVICQSDFS SLEVFIQAIL TGDEQLIADL AAGVDMHCMR LAVKEKMPYE
EVLHLCKGKG VDPEVQSVWD YKRTKAKVFS FQRAYGAGVA KIASSTGMTE EEVQALVDAE
NERYPKIEEF YNRLTATIKK NRKPTSKTIE HPDKRGLMVQ LGKSFSRTPD GKLYCYWESP
SPSYLLDKGV LSSFSPTEIK NYVVQGGGGE WAKAAMWLSV RAFYHFKNFD GKALLVNQVH
DAEYGDFHKS VAAKAAALLH TCMEEASTFM EWWFKWELPI GVPSDTVWGP SMMDEGKIDD
PIFGKAVDKL RPWLRKRFIG GHQPSWLH
//
