ID A0A1S8BBL5_9PEZI Unreviewed; 1931 AA.
AC A0A1S8BBL5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
DE Flags: Fragment;
GN ORFNames=BK809_0000669 {ECO:0000313|EMBL:OMP84917.1};
OS Diplodia seriata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Diplodia.
OX NCBI_TaxID=420778 {ECO:0000313|EMBL:OMP84917.1, ECO:0000313|Proteomes:UP000190776};
RN [1] {ECO:0000313|EMBL:OMP84917.1, ECO:0000313|Proteomes:UP000190776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F98.1 {ECO:0000313|EMBL:OMP84917.1,
RC ECO:0000313|Proteomes:UP000190776};
RA Robert-Siegwald G., Vallet J., Abou-Mansour E., Xu J., Rey P., Bertsch C.,
RA Rego C., Larignon P., Fontaine F., Lebrun M.-H.;
RT "Draft genome sequence of Diplodia seriata F98.1, a fungal species involved
RT in grapevine trunk diseases.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type III PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00006209}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMP84917.1}.
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DR EMBL; MSZU01000086; OMP84917.1; -; Genomic_DNA.
DR STRING; 420778.A0A1S8BBL5; -.
DR OrthoDB; 147843at2759; -.
DR Proteomes; UP000190776; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05167; PI4Kc_III_alpha; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR001263; PI3K_accessory_dom.
DR InterPro; IPR042236; PI3K_accessory_sf.
DR InterPro; IPR045495; PI4K_N.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF15; PHOSPHATIDYLINOSITOL 4-KINASE ALPHA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00613; PI3Ka; 1.
DR Pfam; PF19274; PI4K_N; 1.
DR SMART; SM00145; PI3Ka; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS51545; PIK_HELICAL; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OMP84917.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000190776};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1378..1552
FT /note="PIK helical"
FT /evidence="ECO:0000259|PROSITE:PS51545"
FT DOMAIN 1625..1915
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OMP84917.1"
SQ SEQUENCE 1931 AA; 215509 MW; 985C5E487F54EE3D CRC64;
SIRRSALEKL ATLSAASPAP DSSSTDFKRL YRLCPPHAQA NGGHDELDGA RGGAARVPMS
LPELETLLAL CKAAPQVVDV ATAEQLLNQL TPYLPESFAQ AIAPSPFLRD LDPSPWEILT
HNLAFAILSL GNNHEGLKEV AAAAVKKYVA EWSASARSLT GEHMSREDAV DNTADGDVGR
VLCLAMSMLG FLSAASACAS IWNPTEMLDL IENLRTALSE KLMISVEASV SNVLYGSNSK
RTLREWRRHA KHYAAMGRPL GALLLHHGLM QVVVACTATV ASPSERESGK PVLDRLQSAH
ALQQPLDAGA ETLLASVAGI AEEELERINA DSEYVKRVGT VWQQHIAHAV LADALVTYLC
CAVLNEEIAD SDKLMDLLES TLSDDILAAD EILACVVLKS MSILGKSSPD HASHLSKSLP
RIIVQGGLKE GTSAVAADCL ASVLMHLPQD AVITTLYSLG NVLSGKQAPE RANTGLSQLN
GGAKANGTLH TQHQTGSTIS LAPADVDEPS HVYGTVIQTI VGVACRCKDQ KISELALSML
VQKIGRVSIS VDAKIIIESS LLGAHSGPGE LRALLKLYSK LARDAIVQDN SVLLDAVMRG
RCHLSREFKV GQPLFEVYLQ YVLDDIVSKG DAHGPEATPM ADTEVAAQEI AQLLGPLAIL
ISSNAEGPEE YIEDEAIVSL QRDAWFNVAV HGFSLTSPLG KRYLNELRIL AQHSKPLVSE
SRADQLESDV ELNTVLRRGK SAEHIVEQKR RLQELLPACE VDIKSLGYPE VVFLNTVHLV
EGLRASTGDC TKTLTYFLDP RLRNKEMGNC MVAIAEAGVR SYLKKTVSGG FQSFSAPYVA
QQLAIFFTGC CHRVLQAQKV AIHCADIIIQ QVPSALCQRA SLFALLELLS MMWNSCLEKE
IDEYGWSSTF TSTRENISIE LSDNYSFRRN TLIQLQNRAR VWVLSAMDIA PLDIKGLLQT
YLSEYDDDGA YGHVSLGRSF ALEMGSVIPS TDQRLGAIDR ERELNINTAS DFVAQYTNRQ
EYRYVEPMTD FNDDWIRFGN DSDPLMRRSK HYDRSVEDAR RVLLDLEQRT LSRKHVSIAE
LRDALRRAAA LLCRSPKDEC AIAHHVVGIP FAAFNKQSIK LGISLWLSII KENPRMESRI
LVEIAENFEK TVRRRLGLFD EHFHHPDPFF VKQEFAQSDR TAIMKRQQHA YNLIAPHFRL
LQFLESHFSA TRLGSPHVER VYHRLMHITL SAMSHTTNHP LTREAHFHVV LLGLRILQYS
TGSNTSGQWR LKDRILSAAL AWFKERPRWS FGGNRLQIKA EAQVLVDIHN ALQNVTGIGL
NTNGPRKSLH AKQELLLLLL ASEHQRLMVW LFPLEQDRRL HLMPGHSGKA PTDAVLSGLL
KTAWTEDPAI AVQLVFRFNS LRLATEVRFL VLNFPEKVLD QPDALEVLLG KSLPDDVSFQ
LKYLMYWAPV NPMTAITYFL PAYGNHPFII QYAMRALESH SVDITFFYVP QVVQTLRYDV
LGYVERYIIE TAKFSQLFAH QIIWNMKANA FKDEDSLIPD PVKPTLDVVM ASLENSFSPE
DREFYEREFT FFNEVTGISG KLKPFIKKSK PEKKQKIEEE LRSIKVEVGV YLPSNPDGVV
VGIDRKSGKP LQSHAKAPYM ATFRIRKEKT EIIPVVEDGN DEEKKEENYY EVWQSAIFKV
GDDCRQDVLA LQMISAFRGI FNDVGLDVYV FPYRVTATAP GCGVIDVLPN SISRDMLGRE
AVNGLYDYFV SKYGGEDSIR FQEARNNFVK SMAAYSIISY LLQFKDRHNG NIMIDDAGHI
LHIDFGFCFD IAPGGIKFER APFKLTQEMV AVMGGSTDSQ PYRWFEELCI KAFLAARQHC
EHLAHIVIVM LDSGLPCFKP ETVQHFRERF VLDKTEREAA EFMRFLIKKS YNSLSTGQYD
RFQLLTNGIP Y
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