ID A0A1S8CXP7_9GAMM Unreviewed; 375 AA.
AC A0A1S8CXP7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN ORFNames=BKE30_04745 {ECO:0000313|EMBL:ONG41415.1};
OS Alkanindiges hydrocarboniclasticus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Alkanindiges.
OX NCBI_TaxID=1907941 {ECO:0000313|EMBL:ONG41415.1, ECO:0000313|Proteomes:UP000192132};
RN [1] {ECO:0000313|EMBL:ONG41415.1, ECO:0000313|Proteomes:UP000192132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H1 {ECO:0000313|EMBL:ONG41415.1,
RC ECO:0000313|Proteomes:UP000192132};
RA Subhash Y., Lee S.;
RT "Draft Genome sequence of Alkanindiges sp. strain H1.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONG41415.1}.
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DR EMBL; MLCN01000010; ONG41415.1; -; Genomic_DNA.
DR RefSeq; WP_076877495.1; NZ_MLCN01000010.1.
DR AlphaFoldDB; A0A1S8CXP7; -.
DR STRING; 1907941.BKE30_04745; -.
DR OrthoDB; 9800864at2; -.
DR UniPathway; UPA00223; UER00717.
DR Proteomes; UP000192132; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06108; Ec2MCS_like; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01800; cit_synth_II; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF25; CITRATE SYNTHASE-RELATED PROTEIN DDB_G0287281; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 261
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 312
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 375 AA; 41674 MW; 17DB3E6D58A5C271 CRC64;
MAEGKVLSGA GLRGQVAGKT ALSTVGKSGA GLTYRGYDVK DLAEHCEFEE VAYLIFFGEL
PNAEQLAAYK AKLKGLRSLP QALKDVLERI PADSHPMDVM RTGCSMLGNL ETEQSFAEQQ
QVTDRLLATF PSIITYWYRF SHDGVRIDEN TDDDSIGAHF LHLLKGEKPN ELHAKVMNVS
LILYAEHEFN ASTFTARVCA STLSDMHSCV TGAIGSLRGP LHGGANEAAM DMIEKFTDPD
HAESEMMAML ARKDKIMGFG HAIYKDNDPR NGIIKQWSEK LAADVGDTVL YPVSVRCEEV
MWREKKLFCN ADFFHASAYH FMGIPTKLFT PIFVMSRLTG WAAHVMEQRA DNRIIRPSAE
YTGPELRSVT PITQR
//
