ID A0A1S8D715_9PROT Unreviewed; 665 AA.
AC A0A1S8D715;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Phenol 2-monooxygenase {ECO:0000313|EMBL:ONH83155.1};
GN ORFNames=APZ41_010805 {ECO:0000313|EMBL:ONH83155.1};
OS Roseomonas mucosa.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Roseomonas.
OX NCBI_TaxID=207340 {ECO:0000313|EMBL:ONH83155.1, ECO:0000313|Proteomes:UP000054844};
RN [1] {ECO:0000313|EMBL:ONH83155.1, ECO:0000313|Proteomes:UP000054844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAVE376 {ECO:0000313|EMBL:ONH83155.1,
RC ECO:0000313|Proteomes:UP000054844};
RA Choudhury M.A., Sidjabat H.E., Wailan A.M., Zhang L., Marsh N.M.,
RA Rickard C.M., Davies M., Mcmillan D.J.;
RT "Draft genome sequence of Roseomonas mucosa strain AU37, isolated from a
RT peripheral intravenous catheter.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONH83155.1}.
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DR EMBL; LLWF02000030; ONH83155.1; -; Genomic_DNA.
DR RefSeq; WP_058390338.1; NZ_LLWF02000030.1.
DR AlphaFoldDB; A0A1S8D715; -.
DR SMR; A0A1S8D715; -.
DR STRING; 207340.APZ41_010805; -.
DR OrthoDB; 9791689at2; -.
DR Proteomes; UP000054844; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:ONH83155.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054844}.
FT DOMAIN 34..406
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 444..608
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
SQ SEQUENCE 665 AA; 72724 MW; EDC9255A10C8FBD5 CRC64;
MQFHLNGFHA GDPEAARVDP PVPGATPAPL PGTTDVLIVG CGPAGLTLAA QLAAFPGIST
RIVEQKAGPL MLGQADGIAC RTMEMFNAFG FAERVLREAY WVNELVFWKP DSTRRDAIYR
SDRIRDTEEG LSEFPHVILN QARVHDFYLE TMRRGASPIV PDYHRRLASL EVSTEPDVSH
PVTARFERLD PGHEGEVEAI RARYAVGCDG ARSAVRREIG LSLEGASANQ AWGVMDVLAV
TDFPDIRLKC VIHSAAGNMV IIPREGGYLV RLYIEMDKLA ENERVASRQI TVDHLIAAAR
RILSPYTLEV KEVAWWSVYE IGQRLCGRFD DVPTAAKATR PPRVFIAGDA CHTHSPKAGQ
GMNVSMQDAF NLGWKLAAVL RGQVDPALLA TYSVERHAVA EELIAFDRKL ARMLSLPPKD
PHDPDSEGVD PAEFQAYFVQ QGRFTAGTAM RYAPSAITGA ATHQHLAEGF AIGMRFHSAP
VIRLADAKPM HLGHTVQADG RWRLFAFAAA EDPAAPSSRI QALCRFLEGD AASPIRRHTP
EGEDIDAVID LRAIFQQPHR ELAFGAMPAL LRPAKGRHGL VDHEKMFCPV VANGQDIFDL
RGIDRGHGCV VIVRPDQHVA HVLSLEDHAG IADFFSAFML NGQQAVPLRD GASKAPLGFS
QQPAL
//
