ID A0A1S8FFH1_9BURK Unreviewed; 925 AA.
AC A0A1S8FFH1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B0B52_15615 {ECO:0000313|EMBL:OOG39439.1};
OS Polaromonas sp. A23.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1944133 {ECO:0000313|EMBL:OOG39439.1, ECO:0000313|Proteomes:UP000218978};
RN [1] {ECO:0000313|EMBL:OOG39439.1, ECO:0000313|Proteomes:UP000218978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A23 {ECO:0000313|EMBL:OOG39439.1,
RC ECO:0000313|Proteomes:UP000218978};
RA Lycus P., Bothun K.L., Bergaust L., Shapleigh J.P., Bakken L.R.,
RA Frostegard A.;
RT "Phenotypic and genotypic richness of denitrifiers revealed by a novel
RT isolation strategy.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOG39439.1}.
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DR EMBL; MUNO01000027; OOG39439.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8FFH1; -.
DR STRING; 1944133.B0B52_15615; -.
DR Proteomes; UP000218978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF24; SENSOR HISTIDINE KINASE RPPB; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000218978};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..925
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012616739"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 495..546
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 573..594
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 620..671
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 689..909
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 656..685
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 925 AA; 102312 MW; AAD70E4BCD6B297C CRC64;
MPFLVLFLLV LLPVSQAHAQ SGKLAIDAEG SYTLSRAFTV LEDSTGQLTL DDVLKPGQQE
RFKPVSQSGS ATNFGLTLSA FWLRINLETQ IDSPAQWLFE VAYPALDQLE LFTPRPHGGY
DRQIGGDLQA FETRKIPHRN HVLPVTLQPG AENVLYLRVQ SQGTLSAPAR LWQPSALWQH
DQAEYAMLSL YFGLLIGLLL YNLLLYFSVR DRAYVIYAGF AGGMALSQAA LTGLGGQFLW
PGLTWWNSVS PPVGMAVTAT FGILFARKFL DSATRMPWMN RVMLALTGGW LLALLAALLL
PYTVSSWMVT VLAVVSVTVV VLAAVLSVLK KCPGARYFLT AWAVLLLGVA TLVLHNTGVL
PSNLLTSNSL LIGSALEMVL LSFALADRIN MERAEKEQAQ AASQADQAMV EALSQSQERY
RTVLQERETI LANSIVGIAF LTPEGRFRWA NQAMLEIFGA GDEPLNSMEP FYLSREQYLR
VGGDVAACIR DGKTYETEIQ VRQYNGTLIW ISLSGKSVSP RDLTQGTVWV MMDITRRKEL
EAELVRTSSE REAILNSALV GIVLSVARRH EWVNEKFAEM MGYPRTELIG RSSMHLHANV
AAWEDFGRQA RDELQRHGTY ACERELRRRN GELFWVQMGG SCLQPNDPDA GVIWTFLDIT
ERKKSEEDTR EALEQQKELN ELRSRFVAMT SHEFRTPLAT ILSSGEILKH YGERLSAPEK
ADVLDSIAAS VQRMMRMLDR VLLIGKAEAQ MLEFDPRPTD LRRLCLDLLE EAQVQQPESA
CELRLDYAGG DEPGLYDEKL LRHILGNLLS NAVKYSPQGG EVLFKVVKEP QAMVLEVSDN
GIGIPEDEIA HLYESFHRAS NVGAIQGTGL GLAIARNAVN VHGGTIDVRS RVGAAASGTC
FTVRLPLAAG VSSSGPSPFR TEVEP
//
