ID   A0A1S8FLY2_9BURK        Unreviewed;       339 AA.
AC   A0A1S8FLY2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE            EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN   ORFNames=B0B52_03640 {ECO:0000313|EMBL:OOG46185.1};
OS   Polaromonas sp. A23.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=1944133 {ECO:0000313|EMBL:OOG46185.1, ECO:0000313|Proteomes:UP000218978};
RN   [1] {ECO:0000313|EMBL:OOG46185.1, ECO:0000313|Proteomes:UP000218978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A23 {ECO:0000313|EMBL:OOG46185.1,
RC   ECO:0000313|Proteomes:UP000218978};
RA   Lycus P., Bothun K.L., Bergaust L., Shapleigh J.P., Bakken L.R.,
RA   Frostegard A.;
RT   "Phenotypic and genotypic richness of denitrifiers revealed by a novel
RT   isolation strategy.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC         [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC         (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC         A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC         ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC         EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC       {ECO:0000256|ARBA:ARBA00043995}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOG46185.1}.
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DR   EMBL; MUNO01000008; OOG46185.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S8FLY2; -.
DR   STRING; 1944133.B0B52_03640; -.
DR   Proteomes; UP000218978; Unassembled WGS sequence.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR   CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR002201; Glyco_trans_9.
DR   InterPro; IPR011910; RfaF.
DR   NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR   PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR   PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR   Pfam; PF01075; Glyco_transf_9; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218978};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OOG46185.1}.
SQ   SEQUENCE   339 AA;  36129 MW;  0A2D426CE2A2C08C CRC64;
     MPTTSRSLIV APQWIGDAVM TEPLLRRLHA RGEQLTVGAL PWVAPVYRAM PQVHEVIEFP
     FAHGGLQLKA RRALAKRIAG QFDSAYILPN SLKSALLPLL AGIPKRIGYL GEARIGLLTH
     RLKNPAKGQR PPMVAFYSAL SGETDLDADR PQLQMPADVV AQALTELGLQ RGAYHVFAPG
     AEYGPAKRWP ARHFSELAQK LALPVLLLGS GKEAALCEEI AVAANAGRPG ACVNLAGKTS
     LIQALCAIAA ARSVVSNDSG LMHVAAAFGV PQVAIFGSSS PLHTPPLSAE ASVLWLKNDP
     AYQPPLDCAP CFERECPLGH TRCLNDINPA RVLQALQVG
//