ID A0A1S8LMX1_9CLOT Unreviewed; 333 AA.
AC A0A1S8LMX1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Phosphate acetyltransferase {ECO:0000256|ARBA:ARBA00021528};
DE EC=2.3.1.8 {ECO:0000256|ARBA:ARBA00012707};
DE AltName: Full=Phosphotransacetylase {ECO:0000256|ARBA:ARBA00031108};
GN Name=pta_1 {ECO:0000313|EMBL:OOL93238.1};
GN ORFNames=CLAUR_007820 {ECO:0000313|EMBL:URZ00794.1}, CROST_023190
GN {ECO:0000313|EMBL:URZ11602.1}, CROST_03740
GN {ECO:0000313|EMBL:OOL93238.1};
OS Clostridium felsineum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=36839 {ECO:0000313|EMBL:OOL93238.1};
RN [1] {ECO:0000313|EMBL:OOL93238.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7320 {ECO:0000313|EMBL:OOL93238.1};
RA Poehlein A., Montoya Solano J.D., Flitsch S., Krabben P., Duerre P.,
RA Daniel R.;
RT "Microbial solvent formation.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:URZ11602.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 7320 {ECO:0000313|EMBL:URZ11602.1};
RA Poehlein A., Schoch T., Duerre P., Daniel R.;
RT "Genome sequence of C. roseum typestrain.";
RL Submitted (APR-2022) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:URZ00794.1, ECO:0000313|Proteomes:UP000190175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 793 {ECO:0000313|EMBL:URZ00794.1,
RC ECO:0000313|Proteomes:UP000190175};
RA Poehlein A., Schoch T., Duerre P., Daniel R.;
RT "Genome sequence of Clostridium aurantibutyricum DSM 793.";
RL Submitted (APR-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000705};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2. {ECO:0000256|ARBA:ARBA00004989}.
CC -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC butyryltransferase family. {ECO:0000256|ARBA:ARBA00005656}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LZYV01000025; OOL93238.1; -; Genomic_DNA.
DR EMBL; CP096988; URZ00794.1; -; Genomic_DNA.
DR EMBL; CP096983; URZ11602.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8LMX1; -.
DR STRING; 84029.CROST_03740; -.
DR KEGG; caun:CLAUR_007820; -.
DR KEGG; crw:CROST_023190; -.
DR Proteomes; UP000190175; Chromosome.
DR Proteomes; UP000190951; Chromosome.
DR GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR InterPro; IPR012147; P_Ac_Bu_trans.
DR InterPro; IPR004614; P_AcTrfase.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR NCBIfam; TIGR00651; pta; 1.
DR PANTHER; PTHR43356; PHOSPHATE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43356:SF3; PHOSPHATE ACETYLTRANSFERASE; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR PIRSF; PIRSF000428; P_Ac_trans; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:OOL93238.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OOL93238.1}.
FT DOMAIN 3..326
FT /note="Phosphate acetyl/butaryl transferase"
FT /evidence="ECO:0000259|Pfam:PF01515"
SQ SEQUENCE 333 AA; 36094 MW; 7E6C23F3F88460C4 CRC64;
MDLMESIWEC AKGDKKRIVL AEGEEKRNLI AADKIIKEGL AEIVLVGNEE NIKANASALN
LDISKAEIMD PEKSNKTEKY ARDFYELRKH KGMTIEKAEK MVRDPLYFAT MALKNDYVDG
MVSGAVHTTG DLLRPGLQII KTAPGVKIVS GFFVMIIPDC DYGEEGLLLF ADCAVNPNPS
SDELADIAIT TAETARKLCK LEPKVAMLSF STMGSAKGEM VDKVRNAVET TKKFRPDLAI
DGELQLDAAI EKEVAALKAP SSNVAGKANV LVFPDLQTGN IGYKLVQRFA KAKAIGPICQ
GFAKPINDLS RGCSADDIVN VVAVTVVQAQ RGI
//
