ID   A0A1S8T4A2_9CLOT        Unreviewed;       414 AA.
AC   A0A1S8T4A2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN   Name=nrgA_2 {ECO:0000313|EMBL:OOM72492.1};
GN   ORFNames=CLPUN_46840 {ECO:0000313|EMBL:OOM72492.1};
OS   Clostridium puniceum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=29367 {ECO:0000313|EMBL:OOM72492.1, ECO:0000313|Proteomes:UP000190890};
RN   [1] {ECO:0000313|EMBL:OOM72492.1, ECO:0000313|Proteomes:UP000190890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2619 {ECO:0000313|EMBL:OOM72492.1,
RC   ECO:0000313|Proteomes:UP000190890};
RA   Poehlein A., Montoya Solano J.D., Flitsch S., Krabben P., Duerre P.,
RA   Daniel R.;
RT   "Microbial solvent formation.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC       family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOM72492.1}.
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DR   EMBL; LZZM01000222; OOM72492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S8T4A2; -.
DR   STRING; 29367.CLPUN_46840; -.
DR   OrthoDB; 9814202at2; -.
DR   Proteomes; UP000190890; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR001905; Ammonium_transpt.
DR   InterPro; IPR018047; Ammonium_transpt_CS.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   NCBIfam; TIGR00836; amt; 1.
DR   PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR   PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   SUPFAM; SSF111352; Ammonium transporter; 1.
DR   PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE   3: Inferred from homology;
KW   Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW   ECO:0000256|RuleBase:RU362002};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190890};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT   TRANSMEM        9..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        98..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        127..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        163..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        228..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        258..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        282..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        312..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        354..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   DOMAIN          9..407
FT                   /note="Ammonium transporter AmtB-like"
FT                   /evidence="ECO:0000259|Pfam:PF00909"
SQ   SEQUENCE   414 AA;  43726 MW;  8AA0ED1B3CAEBD18 CRC64;
     MEINLGDSAF LMICSALVFV MTPGLAFFYA GMVRRKNVLN TLMSSFFICG LASVMWVLIG
     YSLSFGDDVF GIIGGLNFFG FNGVGAEPSA YAPTIPHMLF AAFQMMFAII TPALITGSLI
     GRMKFSALFI FIGLWSLLVY YPMAHMVWGS GGLISSLGAV DFAGGNVVHI SSGVSGLVAC
     IMLGKRRGYG MMSYRPHNIP FVVLGAALLW FGWFGFNAGS ALGAGPLAVH AFMTTNTAAA
     SAMLSWMLIE KIKHGKPTVL GAATGAVVGL VAITPGAGFV PLWTSIIIGA VVSPICFFFM
     GTVKAKFGYD DALDAFGCHG IGGVWGGIAT GLFGQTAINS VAKWNGLFFG DINLLLAQLA
     GIAITIVFAA CMTFIIIKVM KLFMDIRVEK SEEADGLDVA EHGETAYPAF NGLD
//