ID A0A1S8TFA4_9CLOT Unreviewed; 748 AA.
AC A0A1S8TFA4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Helicase IV {ECO:0000313|EMBL:OOM76356.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:OOM76356.1};
GN Name=helD_1 {ECO:0000313|EMBL:OOM76356.1};
GN ORFNames=CLPUN_27430 {ECO:0000313|EMBL:OOM76356.1};
OS Clostridium puniceum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=29367 {ECO:0000313|EMBL:OOM76356.1, ECO:0000313|Proteomes:UP000190890};
RN [1] {ECO:0000313|EMBL:OOM76356.1, ECO:0000313|Proteomes:UP000190890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2619 {ECO:0000313|EMBL:OOM76356.1,
RC ECO:0000313|Proteomes:UP000190890};
RA Poehlein A., Montoya Solano J.D., Flitsch S., Krabben P., Duerre P.,
RA Daniel R.;
RT "Microbial solvent formation.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOM76356.1}.
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DR EMBL; LZZM01000174; OOM76356.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8TFA4; -.
DR STRING; 29367.CLPUN_27430; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000190890; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR CDD; cd01983; SIMIBI; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR048228; HelD_bacillota.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; NF041464; HelD_BACSU; 1.
DR PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000190890}.
FT DOMAIN 201..607
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 222..229
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 748 AA; 87170 MW; C11C375E6F66C9DF CRC64;
MDTQLDFLRE ENKLNEILEI LNKEILSYLD RRKNVTKYIL DSRKKYIEDY KDDEDQVIDY
FDHENYVQEE AYKTIDKRLM EYTKLKEVPY FGKITFKEDE DVPEDMYIGR YGLTLEDSYE
PLIVDWRAPI AALFYKGTLG EASYNPPSGE RTADILSRKQ LIIKKGQLKG VFDSALDVKD
EILQMVLTEN SSDKLKDIVM TIQKEQDEII REDRNKIVVV NGVAGSGKTT IALHRISYLL
YNFRKQFGDK VLIFGPNDIF MDYIAQVLPS LGEGNIKQTT FENFVKKELG LEHEKLKSFE
SYIEDAMNGN EEVLKEYQYK TSKKFVQLLD LIIETLEKEY FKIKSVKFKD EEIVSIKDII
ELFTVYYKDM PLFRRSEKIR RILTSKIKDK RDEEVYKINA EMKEKINNLS EEELEIEKGN
IEYLRKIKIR ETIREVINSR NELDAWLKVE PVMDIYKKII GSGICNGKKE AFEKMDMNSL
SKILSERMGV DFPLEKEKNY NVIDESIINL GYLDLVGVLY LSIKLQGLKV KSEIKHVVID
EAQDYSFIQF EIIKGMTGCN SYTIVGDSNQ RLITIDEEPA MLHLDEIFKD SKAEIKPYDL
NKSYRSTQEI MEYANQFVDE DRIVPLVRNG EPVIEEKVSS KEDFIDTLLS IVEDYEEEGL
ENIAVIFKDK RELAEYAPLV KEKISIQSLD NEDVVYKGGK VLLPAYLAKG LEFDGVVVVD
NKEIQPLLKY IMCTRALHRL SVIETLVL
//
