ID   A0A1S8VP75_9FUNG        Unreviewed;       931 AA.
AC   A0A1S8VP75;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BSLG_05714 {ECO:0000313|EMBL:OON04125.1};
OS   Batrachochytrium salamandrivorans.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC   Rhizophydiales incertae sedis; Batrachochytrium.
OX   NCBI_TaxID=1357716 {ECO:0000313|EMBL:OON04125.1, ECO:0000313|Proteomes:UP000189906};
RN   [1] {ECO:0000313|EMBL:OON04125.1, ECO:0000313|Proteomes:UP000189906}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BS {ECO:0000313|EMBL:OON04125.1,
RC   ECO:0000313|Proteomes:UP000189906};
RA   Lavstsen T., Jespersen J.S.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC       {ECO:0000256|ARBA:ARBA00007779}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OON04125.1}.
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DR   EMBL; LYON01001138; OON04125.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S8VP75; -.
DR   STRING; 1357716.A0A1S8VP75; -.
DR   VEuPathDB; FungiDB:BSLG_05714; -.
DR   OrthoDB; 1330110at2759; -.
DR   Proteomes; UP000189906; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR   InterPro; IPR045122; Csc1-like.
DR   InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR   InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR   InterPro; IPR032880; Csc1/OSCA1-like_N.
DR   PANTHER; PTHR13018:SF154; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED; 1.
DR   PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR   Pfam; PF14703; PHM7_cyt; 1.
DR   Pfam; PF02714; RSN1_7TM; 1.
DR   Pfam; PF13967; RSN1_TM; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189906};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        585..618
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        640..665
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        677..697
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          11..174
FT                   /note="CSC1/OSCA1-like N-terminal transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF13967"
FT   DOMAIN          198..373
FT                   /note="CSC1/OSCA1-like cytosolic"
FT                   /evidence="ECO:0000259|Pfam:PF14703"
FT   DOMAIN          384..658
FT                   /note="CSC1/OSCA1-like 7TM region"
FT                   /evidence="ECO:0000259|Pfam:PF02714"
FT   REGION          820..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        907..921
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   931 AA;  102678 MW;  7FDE69243EAA770C CRC64;
     MTAVYSDLIS LLTAFGTNIA ISAGLVIGFS LLRPTNKNVY EPRRKFAEEQ KRPEALSANP
     ISWLKPAYAI DEIHMVNKIG LDAVMFLRFI KVLVKLFCGT SILAVILCAI NFHSPSIDPP
     ISSGNGDGAD SVAFNPSLTL FSISNMTNPE SQLFYIPAIF AWIISGYAYL LLYTTWSEYI
     DLRKKYFSSP EYLHSYHSRC LLVTDIPESM HKEGALKEFV NSAGLSYPAT QVLIGRNFEN
     LPQLMKEHTA ATLALEGVFV KYLKDPYNLP SERPTHKIGG YIFHLIGGTK VDSIDHYGKE
     IRRLESSIYE LRSKGDQYFK PNSSAFISFD TIKGSHSAAH KLSGFISTSI RTQSITPPRF
     KMCPNFEQLI WENVGVLSAV RNTRRLIAMG MLVVITIGWT FFQAFLGTLI TIESIASYSP
     AVAGFISRNQ ALNVIVKSFV GPGLVALSNI LLPMALRVVA RTQGVVSVSG VEKSVLYKYF
     VFQVYNQLII NVVGITGVKG VWNALTNGGG SNKQIWQQVA TDIVARGNVV LLYIIAGYTS
     YGVEIIQGAP LVIGYIKRRY FTLTPRQEYE LNDEPEFDFM ITYGFLTLVA LIGLGYSVIA
     PIIVPFVTIL FILAYVVMKY QLLYVYEVKN ETGGTWWPKV FNILCLIIGA FQLMTFGSIV
     VTAAAKSIRG NGKSQSLLVV VLPFITIAFY LYCSFYLSPQ AQYVSKLHTS AFSPYNPNGN
     SSLASSTDGK LENESEEDAL ANRVFNPAIV KPLTKVWVNK LAKDLLSTYY RPEYVDLVDY
     VRKTKTGASR DTYLSNAREV KKRMVSFQAI SGVTTRLGRT RSIKRDQQRA YGSADAEEAG
     MTLDDASELD LPPEDSPISL TPVDSYAEGL ARPRQPSSGY VGPIGGSANR GDGPDAYEMM
     PVESGHSSGG GSRNGSSGHV PTSGVMAYHK R
//