ID A0A1S8VW38_9FUNG Unreviewed; 758 AA.
AC A0A1S8VW38;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Ribosome biogenesis protein ERB1 {ECO:0000256|HAMAP-Rule:MF_03027};
DE AltName: Full=Eukaryotic ribosome biogenesis protein 1 {ECO:0000256|HAMAP-Rule:MF_03027};
GN Name=ERB1 {ECO:0000256|HAMAP-Rule:MF_03027};
GN ORFNames=BSLG_03927 {ECO:0000313|EMBL:OON06397.1};
OS Batrachochytrium salamandrivorans.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=1357716 {ECO:0000313|EMBL:OON06397.1, ECO:0000313|Proteomes:UP000189906};
RN [1] {ECO:0000313|EMBL:OON06397.1, ECO:0000313|Proteomes:UP000189906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS {ECO:0000313|EMBL:OON06397.1,
RC ECO:0000313|Proteomes:UP000189906};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the NOP7 complex, which is required for
CC maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBUNIT: Component of the NOP7 complex, composed of ERB1, NOP7 and
CC YTM1. Within the NOP7 complex ERB1 appears to interact directly with
CC NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON06397.1}.
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DR EMBL; LYON01000582; OON06397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8VW38; -.
DR STRING; 1357716.A0A1S8VW38; -.
DR VEuPathDB; FungiDB:BSLG_03927; -.
DR OrthoDB; 5472008at2759; -.
DR Proteomes; UP000189906; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR17605:SF0; RIBOSOME BIOGENESIS PROTEIN BOP1; 1.
DR PANTHER; PTHR17605; RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03027};
KW Reference proteome {ECO:0000313|Proteomes:UP000189906};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 156..414
FT /note="BOP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01035"
FT REPEAT 421..462
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 14..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..109
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 86194 MW; 82C2CBD6E8C5D62C CRC64;
MARKRSLETL AKVAKLESDG NDNEEYDFEA INESESNASD SSDVADRSTV KDDEDTGSNA
LFLSTSNDEG DEDNESEEEI DNSDDEEFYG DDTDYFSGGD LDSDEEEDDV VGQPAKKGSF
KVVRRADMPD IDPVYLSDTS DEDNYNTVGN IPMEWYDDFP HIGYDIDGKK IMRPAKGDEL
DAFLSVMEDK DSWRSVYDKM KGKDMQLSRE ELNTLKKIHS HEFPDSGFDP YAPTIEWFTS
KAETMPLSAA PEPKSRFIPS KIEAAKIMKI ARAIRAGLIL PAHKKKSKAL EKPKFYDIWE
SAPDETIRPN HITAPKMAPP EHMQSYNPPA EYLYSKEEEK KWMETDPESR FRNFVPRKYS
SLRQVPAYDR FIQERFTRCL DLYLCPRTIK KKLDIDPESL IPKLPKPQDL LPFPTKLSVE
YKGHESRVRS ISVSASGQWL ATGSDDKTLR IWEVSSGRCV EKFELEHSVM SVSWNPNKSV
SLLAVAFDTQ IALIVPTQIN QALQDATVDL ISDIWAQTGE RNKSCEWSKP NEDEQRQGYR
ARIMLTKGIT TLNWHHKGDY LATVSPDAAT NAVQIHQIST GRSQTPFRKS KGLVQQVLFH
PLKPIIFVAT QRYIRVYNLA KQELVRKLLP GAKWISSMDI HPGGDNLIVG TYDKRIHWFD
MDLSSQPYKT LRFHREAVRQ VAFHKRYPLF ASSSDDGSVL VFHGMVYNDL MQNPLIVPVK
SLKAHKPVSH LGALSCQFHP TQPWLFTCGA DGAVKLFC
//
